Quinazolines are considered as a promising class of bioactive heterocyclic compounds with
broad properties. Particularly, the quinazoline scaffold has an impressive role in the design …

Epilepsy is one of the most frequent chronic neurological disorder extremely threatening the
life and good health. More than 70 million individuals suffering from epilepsy worldwide and …

Here in, we report the design, synthesis and in vitro anticancer activity of a novel series of 24
quinoline analogues of substituted amide and sulphonamide derivatives. The anticancer …

New substituted quinoline derivatives were designed and synthesized via a five-step
modified Suzuki coupling reaction. A comparative molecular docking study was carried out …

Two different schemes of novel substituted quinoline derivatives were designed and
synthesized via simple reaction steps and conditions. A comparative molecular docking …

Two novel compounds [Ni (PQC) 2 (H 2 O) 2]. H 2 O and [Cu (PQC) 2] where PQC= 2–
phenylquinazoline–4–carboxylate have been synthesized. Magnetic susceptibility …

Magnetic Cu-MOF-74 (Fe3O4@ SiO2@ Cu-MOF-74) was synthesized for the first time by
grafting MOF-74 (copper as the metal center) on the surface of core-shell magnetic carboxyl …

Quinolones, a key class of heterocyclics, are gaining popularity among organic and
medicinal chemists due to their promising properties. Quinoline, with its broad spectrum of …

Targeting kinases with oncogenic driver mutations in malignancies with allosteric kinase
inhibitors is a promising new treatment technique. EGFR inhibitors targeting the …

Mechanisms for formation and hydrolysis of biologically active 2-substituted [1, 2, 4] triazolo
[1, 5-c] quinazolines were modeled at the SMD/B3LYP/6–31+ G (d) theory level. Obtained …