Heaves, an asthma‐like disease of horses

M Leclere, A LAVOIE‐LAMOUREUX, JP LAVOIE - Respirology, 2011 - Wiley Online Library
Animal models have been developed to investigate specific components of asthmatic airway
inflammation, hyper‐responsiveness or remodelling. However, all of these aspects are …

Highlights of progress in silage conservation and future perspectives

JM Wilkinson, M Rinne - Grass and Forage Science, 2018 - Wiley Online Library
Highlights of progress in the production of silage over the past 50 years include the
introduction of improved hybrids of maize (Zea mays L.), the forage harvester, the big baler …

Inflammatory airway disease of horses

LL Couëtil, AM Hoffman, J Hodgson… - Journal of veterinary …, 2007 - Wiley Online Library
The purpose of this consensus statement is to provide a review of current knowledge and
opinions concerning inflammatory airway disease (IAD) and to help practitioners …

Recurrent airway obstruction: a review

RS Pirie - Equine veterinary journal, 2014 - Wiley Online Library
Recurrent airway obstruction is a widely recognised airway disorder, characterised by
hypersensitivity‐mediated neutrophilic airway inflammation and lower airway obstruction in …

Neutrophilic airway inflammation in horses with heaves is characterized by a Th2-type cytokine profile

JP Lavoie, K Maghni, M Desnoyers, R Taha… - American journal of …, 2001 - atsjournals.org
Heaves in horses shares many similarities with human asthma, including lower airway
inflammation, reversible airway obstruction, and bronchial hyperresponsiveness. Extrinsic …

Ten years of the horse reference genome: insights into equine biology, domestication and population dynamics in the post‐genome era

T Raudsepp, CJ Finno, RR Bellone… - Animal …, 2019 - Wiley Online Library
The horse reference genome from the Thoroughbred mare Twilight has been available for a
decade and, together with advances in genomics technologies, has led to unparalleled …

Cytokine induction in pulmonary airways of horses with heaves and effect of therapy with inhaled fluticasone propionate

S Giguère, L Viel, E Lee, RJ MacKay… - Veterinary immunology …, 2002 - Elsevier
Work in humans and laboratory animals has identified a central role for cytokines and
chemokines in development and persistence of lower airway inflammation. The objectives of …

The many faces of airway inflammation: asthma and chronic obstructive pulmonary disease

PM O'byrne, DS Postma - American journal of respiratory and critical …, 1999 - atsjournals.org
Airway diseases, predominantly asthma and chronic obstructive pulmonary disease
(COPD), are among the world's most prevalent diseases. The prevalence of asthma has …

Total and respirable airborne dust endotoxin concentrations in three equine management systems

BC McGorum, J Ellison, RT Cullen - Equine veterinary journal, 1998 - Wiley Online Library
The concentrations of total and respirable airborne endotoxin in the breathing zone of a
pony in 3 different management systems, on 8 occasions, are reported. Airborne endotoxin …

Inhaled endotoxin and organic dust particulates have synergistic proinflammatory effects in equine heaves (organic dust‐induced asthma)

RS Pirie, DDS Collie, PM Dixon… - … & Experimental Allergy, 2003 - Wiley Online Library
Background Equine heaves is a naturally occurring organic dust‐induced asthma
characterized by airway neutrophilia, mucus hypersecretion and obstructive lung …