Background This review focuses on exosomes derived from various cancer cells. The review
discusses the possibility of differentiating macrophages in alternatively activated anti …

Insulin-like growth factor-binding proteins (IGFBPs) 1–6 bind IGFs but not insulin with high
affinity. They were initially identified as serum carriers and passive inhibitors of IGF actions …

Gliomas are primary, diffusely infiltrating brain tumors. Microglia are innate immune cells in
the CNS and make up a substantial portion of the tumor mass. Glioma cells shape their …

The prognosis for glioblastoma (GBM) remains depressingly low. The biological barriers of
the brain present a major challenge to achieving adequate drug concentrations for GBM …

ABSTRACT Preclinical Research MicroRNAs (miRNAs) are small endogenous noncoding
RNAs that suppress gene expression at the post‐transcriptional level. In the past decade …

Acne vulgaris, an epidemic inflammatory skin disease of adolescence, is closely related to
Western diet. Three major food classes that promote acne are: 1) hyperglycemic …

Glioblastoma multiforme (GBM) is the most common, malignant, poorly promising primary
brain tumor. GBM is characterized by an infiltrating growth nature, abundant vascularization …

Epithelial-mesenchymal transition (EMT) is a major event during cancer progression and
metastasis; however, the definitive role of EMT in remodeling tumor microenvironments …

Glioblastoma multiforme (GBM) is the most common and lethal cancer of the adult brain,
remaining incurable with a median survival time of only 15 months. In an effort to identify …

Malignant gliomas are the most common and deadly type of central nervous system tumors.
Despite some advances in treatment, the mean survival time remains only about 1.25 years …