Recent advances in the knowledge of the mechanisms of leptin physiology and actions in neurological and metabolic pathologies

ME Casado, R Collado-Pérez, LM Frago… - International Journal of …, 2023 - mdpi.com
Excess body weight is frequently associated with low-grade inflammation. Evidence
indicates a relationship between obesity and cancer, as well as with other diseases, such as …

Epigenetics in precision nutrition

X Li, L Qi - Journal of Personalized Medicine, 2022 - mdpi.com
Precision nutrition is an emerging area of nutrition research, with primary focus on the
individual variability in response to dietary and lifestyle factors, which are mainly determined …

Impact of individual factors on DNA methylation of drug metabolism genes: A systematic review

J Bian, J Zhao, Y Zhao, X Hao, S He… - Environmental and …, 2023 - Wiley Online Library
Individual differences in drug response have always existed in clinical treatment. Many non‐
genetic factors show non‐negligible impacts on personalized medicine. Emerging studies …

Differential DNA methylation of steatosis and non-alcoholic fatty liver disease in adolescence

PE Melton, MA Burton, KA Lillycrop, KM Godfrey… - Hepatology …, 2023 - Springer
Background and aims Epigenetic modifications are associated with hepatic fat accumulation
and non-alcoholic fatty liver disease (NAFLD). However, few epigenetic modifications …

MSI2 Modulates Unsaturated Fatty Acid Metabolism by Binding FASN in Bovine Mammary Epithelial Cells

CC Lyu, Y Meng, HY Che, JL Suo, YT He… - Journal of Agricultural …, 2023 - ACS Publications
The regulation of fatty acid metabolism is crucial for milk flavor and quality. Therefore, it is
important to explore the genes that play a role in fatty acid metabolism and their …

DNA methylome in visceral adipose tissue can discriminate patients with and without colorectal cancer

AG Izquierdo, H Boughanem, A Diaz-Lagares… - Epigenetics, 2022 - Taylor & Francis
Adipose tissue dysfunction, particularly the visceral (VAT) compartment, has been proposed
to play a relevant role in colorectal cancer (CRC) development and progression. Epigenetic …

Adiponectin related vascular and cardiac benefits in obesity: is there a role for an epigenetically regulated mechanism?

RA Fontanella, L Scisciola, MR Rizzo… - Frontiers in …, 2021 - frontiersin.org
In obesity, several epigenetic modifications, including histones remodeling, DNA
methylation, and microRNAs, could accumulate and determine increased expression of …

Novel insights into the whole-blood DNA methylome of asthma in ethnically diverse children and youth

E Herrera-Luis, C Rosa-Baez… - European …, 2023 - Eur Respiratory Soc
Background The epigenetic mechanisms of asthma remain largely understudied in African
Americans and Hispanics/Latinos, two populations disproportionately affected by asthma …

[HTML][HTML] Comparative transcriptome sequencing and weighted coexpression network analysis reveal growth-related hub genes and key pathways in the Chinese soft …

G Chen, T Zhou, J Cao, G Zou, H Liang - Water Biology and Security, 2024 - Elsevier
The Chinese soft-shelled turtle (Pelodiscus sinensis) exhibits sexual dimorphism. Compared
with females, males are considered to have higher economic value due to their accelerated …

Developmental origins of psycho-cardiometabolic multimorbidity in adolescence and their underlying pathways through methylation markers: a two-cohort study

P Choudhary, J Ronkainen, J Carson… - European Child & …, 2024 - Springer
Understanding the biological mechanisms behind multimorbidity patterns in adolescence is
important as they may act as intermediary risk factor for long-term health. We aimed to …