Beneficial effects of adiponectin on glucose and lipid metabolism and atherosclerotic progression: mechanisms and perspectives

H Yanai, H Yoshida - International journal of molecular sciences, 2019 - mdpi.com
Circulating adiponectin concentrations are reduced in obese individuals, and this reduction
has been proposed to have a crucial role in the pathogenesis of atherosclerosis and …

Effects of sodium-glucose co-transporter 2 inhibitors on vascular cell function and arterial remodeling

W Durante, G Behnammanesh, KJ Peyton - International journal of …, 2021 - mdpi.com
Cardiovascular disease is the leading cause of morbidity and mortality in diabetes. Recent
clinical studies indicate that sodium-glucose co-transporter 2 (SGLT2) inhibitors improve …

Metabolic-Dysfunction-Associated Steatotic Liver Disease—Its Pathophysiology, Association with Atherosclerosis and Cardiovascular Disease, and Treatments

H Yanai, H Adachi, M Hakoshima, S Iida… - International journal of …, 2023 - mdpi.com
Metabolic-dysfunction-associated steatotic liver disease (MASLD) is a chronic liver disease
that affects more than a quarter of the global population and whose prevalence is increasing …

SGLT2 inhibitors: are they safe?

S Filippas-Ntekouan, TD Filippatos… - Postgraduate …, 2018 - Taylor & Francis
Sodium–glucose linked transporter type 2 (SGLT2) inhibitors are a relatively new class of
antidiabetic drugs with positive cardiovascular and kidney effects. The aim of this review is to …

Empagliflozin inhibits macrophage inflammation through AMPK signaling pathway and plays an anti-atherosclerosis role

J Fu, H Xu, F Wu, Q Tu, X Dong, H Xie, Z Cao - International Journal of …, 2022 - Elsevier
Objective In recent years, some authoritative clinical studies have found that SGLT2 inhibitor
can reduce cardiovascular risk in patients with diabetes, which may imply that SGLT2 …

Multi-organ protective effects of sodium glucose cotransporter 2 inhibitors

H Yanai, M Hakoshima, H Adachi… - International Journal of …, 2021 - mdpi.com
Sodium glucose cotransporter 2 inhibitors (SGLT2i) block the reabsorption of glucose by
inhibiting SGLT2, thus improving glucose control by promoting the renal excretion of …

Cardiovascular outcomes of sodium-glucose cotransporter 2 inhibitors: a comprehensive review of clinical and preclinical studies

RK Ghosh, D Bandyopadhyay, A Hajra… - International journal of …, 2016 - Elsevier
Diabetes is a leading cause of morbidity and mortality worldwide. Management of diabetes
is changing at a rapid pace. Three new classes of antidiabetic drugs including GLP-1 …

Sodium-glucose cotransporter 2 inhibitors (SGLT2i): their role in cardiometabolic risk management

N Katsiki, D P. Mikhailidis… - Current pharmaceutical …, 2017 - benthamdirect.com
Background: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are a novel category of
oral antidiabetic drugs that inhibit renal glucose reabsorption and increase renal glucose …

Real-World Efficacy of Glucagon-like Peptide-1 (GLP-1) Receptor Agonist, Dulaglutide, on Metabolic Parameters in Japanese Patients with Type 2 Diabetes: A …

H Katsuyama, M Hakoshima, S Umeyama, S Iida… - Biomedicines, 2023 - mdpi.com
The glucagon-like peptide-1 receptor agonist (GLP-1RA) dulaglutide has been shown to
improve body weight and glycemic control and reduce major cardiovascular (CV) events. In …

[HTML][HTML] Retrospective Longitudinal Observational Study on the Long-Term Effects of Sodium-Glucose Cotransporter-2 Inhibitors on the Development of Metabolic …

H Katsuyama, S Horinaka, M Hakoshima… - Journal of Clinical …, 2024 - mdpi.com
Background/Objectives: The health burden of metabolic dysfunction-associated fatty liver
disease (MASLD) has been increasing lately. Cardiovascular disease (CVD) is the main …