Abstract Structure and function are highly correlated in the vertebrate retina, a sensory tissue
that is organized into cell layers with microcircuits working in parallel and together to encode …

The nervous system is populated by numerous types of neurons, each bearing a dendritic
arbor with a characteristic morphology. These type-specific features influence many aspects …

The human brain is a tissue of vast complexity in terms of the cell types it comprises.
Conventional approaches to classifying cell types in the human brain at single cell …

The highly complex structure of the human brain is strongly shaped by genetic influences.
Subcortical brain regions form circuits with cortical areas to coordinate movement, learning …

Background CHD8 (chromodomain helicase DNA-binding protein 8), which codes for a
member of the CHD family of ATP-dependent chromatin-remodeling factors, is one of the …

Subcortical brain structures are integral to motion, consciousness, emotions and learning.
We identified common genetic variation related to the volumes of the nucleus accumbens …

A localized transcriptome at the synapse facilitates synapse-, stimulus-and transcript-specific
local protein synthesis in response to neuronal activity. While enzyme-mediated mRNA …

In the retina, like in most other brain regions, developing neurons are arranged into distinct
layers giving the mature tissue its stratified appearance. This process needs to be highly …

Hearing and balance use hair cells in the inner ear to transform mechanical stimuli into
electrical signals. Mechanical force from sound waves or head movements is conveyed to …

The neural retina, at the back of the eye, is a fascinating system to use to discover how cells
form tissues in the context of the developing nervous system. The retina is the tissue …