Cardiotoxicity of anthracyclines

D Cardinale, F Iacopo, CM Cipolla - Frontiers in cardiovascular …, 2020 - frontiersin.org
Cardiotoxicity is a feared side effect that may limit the clinical use of anthracyclines. It may
indeed affect the quality of life and survival of patients with cancer, regardless of oncological …

Cardiovascular disease and breast cancer: where these entities intersect: a scientific statement from the American Heart Association

LS Mehta, KE Watson, A Barac, TM Beckie, V Bittner… - Circulation, 2018 - Am Heart Assoc
Cardiovascular disease (CVD) remains the leading cause of mortality in women, yet many
people perceive breast cancer to be the number one threat to women's health. CVD and …

Human and animal dirofilariasis: the emergence of a zoonotic mosaic

F Simón, M Siles-Lucas, R Morchón… - Clinical microbiology …, 2012 - Am Soc Microbiol
Dirofilariasis represents a zoonotic mosaic, which includes two main filarial species
(Dirofilaria immitis and D. repens) that have adapted to canine, feline, and human hosts with …

Cardiac injury associated with severe disease or ICU admission and death in hospitalized patients with COVID-19: a meta-analysis and systematic review

X Li, X Pan, Y Li, N An, Y Xing, F Yang, L Tian, J Sun… - Critical care, 2020 - Springer
Background Cardiac injury is now a common complication of coronavirus disease (COVID-
19), but it remains unclear whether cardiac injury-related biomarkers can be independent …

Cardiac troponins in dogs and cats

R Langhorn, JL Willesen - Journal of veterinary internal …, 2016 - Wiley Online Library
Cardiac troponins are sensitive and specific markers of myocardial injury. The troponin
concentration can be thought of as a quantitative measure of the degree of injury sustained …

Micromolded gelatin hydrogels for extended culture of engineered cardiac tissues

ML McCain, A Agarwal, HW Nesmith, AP Nesmith… - Biomaterials, 2014 - Elsevier
Defining the chronic cardiotoxic effects of drugs during preclinical screening is hindered by
the relatively short lifetime of functional cardiac tissues in vitro, which are traditionally …

Drug attrition during pre-clinical and clinical development: understanding and managing drug-induced cardiotoxicity

N Ferri, P Siegl, A Corsini, J Herrmann… - Pharmacology & …, 2013 - Elsevier
Cardiovascular toxicity remains a major cause of concern during preclinical and clinical
development as well as contributing to post-approval withdrawal of medicines. This issue is …

[图书][B] Animal clinical chemistry: a practical handbook for toxicologists and biomedical researchers

GO Evans - 2009 - taylorfrancis.com
10+ Years of Updates Since First EditionNewcomers to the animal clinical chemistry and
toxicology fields quickly find that the same rules of human medicine do not always apply …

Role of biomarkers in chemotherapy-induced cardiotoxicity

D Cardinale, MT Sandri - Progress in cardiovascular diseases, 2010 - Elsevier
Chemotherapy-induced cardiotoxicity remains an unresolved problem strongly impacting
the quality of life and the overall survival of cancer patients. The main strategy for minimizing …

Anticancer drugs and cardiotoxicity: insights and perspectives in the era of targeted therapy

E Raschi, V Vasina, MG Ursino, G Boriani… - Pharmacology & …, 2010 - Elsevier
Drug-induced cardiotoxicity is emerging as an important issue among cancer survivors. For
several decades, this topic was almost exclusively associated with anthracyclines, for which …