Pathophysiology, cellular and molecular mechanisms of large and small vessel diseases

J Koueik, UV Wesley, RJ Dempsey - Neurochemistry International, 2023 - Elsevier
Cerebrovascular disease (CVD) is the second most common cause of cognitive impairment
and dementia in aged population. CVD presents in a myriad number of clinical ways based …

Histopathologic validation of grayscale carotid plaque characteristics related to plaque vulnerability

CC Mitchell, JH Stein, TD Cook, S Salamat… - Ultrasound in medicine …, 2017 - Elsevier
Inflammation and angiogenesis play major roles in carotid plaque vulnerability. The purpose
of this study was to determine whether gray-scale features of carotid plaques are associated …

[HTML][HTML] Ultrasound vascular elastography as a tool for assessing atherosclerotic plaques–a systematic literature review

B Mahmood, C Ewertsen, J Carlsen… - Ultrasound …, 2016 - thieme-connect.com
Atherosclerosis is a widespread disease that accounts for nearly 3-quarters of deaths due to
cardiovascular disease. Ultrasound elastography might be able to reliably identify …

Carotid artery plaque vulnerability assessment using noninvasive ultrasound elastography: validation with MRI

MH Roy Cardinal, MHG Heusinkveld… - American journal of …, 2017 - Am Roentgen Ray Soc
OBJECTIVE. Vulnerable and nonvulnerable carotid artery plaques have different tissue
morphology and composition that may affect plaque biomechanics. The objective of this …

Carotid atherosclerotic plaque instability and cognition determined by ultrasound-measured plaque strain in asymptomatic patients with significant stenosis

RJ Dempsey, T Varghese, DC Jackson, X Wang… - Journal of …, 2017 - thejns.org
OBJECTIVE This article describes the use of ultrasound measurements of physical strain
within carotid atherosclerotic plaques as a measure of instability and the potential for …

[HTML][HTML] Assessment of cognitive function in female rheumatoid arthritis patients: associations with cerebrovascular pathology, depression and anxiety

C Oláh, Z Kardos, M Andrejkovics, E Szarka… - Rheumatology …, 2020 - Springer
We assessed cognitive function of female rheumatoid arthritis (RA) patients and analyze the
determinants, with special focus on cerebrovascular morphology. Sixty methotrexate (MTX-) …

Optimal cardiovascular health is associated with slower cognitive decline

NV Ferreira, NG Gonçalves, C Szlejf… - European Journal of …, 2024 - Wiley Online Library
Abstract Background Life's Simple 7, a lifestyle and cardiovascular index associated with
cognition, has been updated to Life's Essential 8 (LE8) to include sleep. LE8 has been …

Carotid plaque vulnerability assessment using ultrasound elastography and echogenicity analysis

G Cloutier, MHR Cardinal, Y Ju… - American journal of …, 2018 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study was to evaluate ultrasound elastography and
echogenicity analysis to discriminate between carotid plaques in patients with symptomatic …

Classification of symptomatic and asymptomatic patients with and without cognitive decline using non-invasive carotid plaque strain indices as biomarkers

X Wang, DC Jackson, CC Mitchell, T Varghese… - Ultrasound in medicine …, 2016 - Elsevier
Vascular cognitive decline may be caused by micro-emboli generated by carotid plaque
instability. We previously found that maximum strain indices in carotid plaque were …

Non-invasive identification of vulnerable atherosclerotic plaques using texture analysis in ultrasound carotid elastography: An in vivo feasibility study validated by …

C Huang, Q He, M Huang, L Huang, X Zhao… - Ultrasound in Medicine …, 2017 - Elsevier
The aims of this study were to quantify the textural information of strain rate images in
ultrasound carotid elastography and evaluate the feasibility of using the textural features in …