MicroRNAs (miRNAs), a highly conserved class of tissue specific, small non-protein coding
RNAs maintain cell homeostasis by negative gene regulation. Proper controlling of miRNA …

Background Reliable prognostic biomarkers to distinguish indolent from aggressive prostate
cancer (PCa) are lacking. Many studies investigated microRNAs (miRs) as PCa prognostic …

Background Circulating cell-free miRNAs have emerged as promising minimally-invasive
biomarkers for early detection, prognosis and monitoring of cancer. They can exist in the …

MicroRNAs (miRNAs) are non-coding small RNAs that are master regulators of genic
expression and consequently of many cellular processes. But their expression is often …

Prostate cancer (PCa) is the second most common cancer in men worldwide. A large
proportion of PCa are latent, never destined to progress or affect the patients' life. It is of …

Prostate specific antigen (PSA) remains the most used biomarker in the management of
early prostate cancer (PCa), in spite of the problems related to false positive results and …

Circulating nucleic acids are found in free form in body fluids and may serve as minimally
invasive tools for cancer diagnosis and prognosis. Only a few studies have investigated the …

MicroRNAs (miRNAs) are secreted by cells in vesicles, bound in a ribonucleoprotein
complex or as free molecules. These miRNA secretion pathways are dysregulated in cancer …

Abstract microRNAs (miRNAs) are small non-coding RNAs that control gene expression
posttranscriptionally and are part of the giant non codifying genoma. Cumulating data …

Prostate cancer is the most common malignancy among men in the US. Though
considerable improvement in the diagnosis of prostate cancer has been achieved in the past …