Over the past decade, knowledge of the pathogenesis and natural history of type 1 diabetes
has grown substantially, particularly with regard to disease prediction and heterogeneity …

Type 1 diabetes (T1D) is an autoimmune disease mediated by a combination of genetic and
environmental triggers resulting in lymphocytic infiltration of pancreatic islets, destruction of …

OBJECTIVE We investigated whether measuring autoantibodies against zinc transporter 8
(ZnT8A) and IA-2β (IA-2βA) may improve classification of new-onset type 1 diabetic patients …

Type 1 diabetes is a common, severe chronic autoimmune disease that is characterized by
the progressive and insidious loss of self-tolerance to the insulin-producing pancreatic islet …

Autoantibodies to the islet-specific zinc transporter isoform 8 (ZnT8) are detected in the
majority of type 1 diabetes patients prior to and at clinical diagnosis. The presence of …

Type 1 diabetes (T1D) is a T-cell mediated autoimmune disease characterized by
recognition of pancreatic β-cell proteins as self-antigens, called autoantigens (AAgs) …

We examined whether zinc transporter 8 autoantibodies (ZnT8A; arginine ZnT8-RA,
tryptophan ZnT8-WA, and glutamine ZnT8-QA variants) differed between immigrant and …

Aims To assess the prevalence of ZnT8-ab and its correlation to other autoimmune markers
and diabetic ketoacidosis occurrence in children and adults with T1DM onset. Methods The …

BACKGROUND AND AIMS: Autoantibodies against the zinc transporter 8 (ZnT8A) are
common in type 1 diabetes (T1D). ZnT8A analyses are complicated by the fact that there are …

In patients with new onset hyperglycaemia where the type of diabetes is ambiguous,
diabetes specific autoantibodies are the diagnostic test of choice to distinguish between type …