Human chorionic gonadotropin and early embryogenesis
SP d'Hauterive, R Close, V Gridelet, M Mawet… - International Journal of …, 2022 - mdpi.com
Human chorionic gonadotropin (hCG) has four major isoforms: classical hCG,
hyperglycosylated hCG, free β subunit, and sulphated hCG. Classical hCG is the first …
hyperglycosylated hCG, free β subunit, and sulphated hCG. Classical hCG is the first …
Plasticity of the maternal vasculature during pregnancy
G Osol, NL Ko, M Mandalà - Annual review of physiology, 2019 - annualreviews.org
Maternal cardiovascular changes during pregnancy include an expansion of plasma
volume, increased cardiac output, decreased peripheral resistance, and increased …
volume, increased cardiac output, decreased peripheral resistance, and increased …
A placental model of SARS-CoV-2 infection reveals ACE2-dependent susceptibility and differentiation impairment in syncytiotrophoblasts
J Chen, JA Neil, JP Tan, R Rudraraju, M Mohenska… - Nature Cell …, 2023 - nature.com
SARS-CoV-2 infection causes COVID-19. Several clinical reports have linked COVID-19
during pregnancy to negative birth outcomes and placentitis. However, the …
during pregnancy to negative birth outcomes and placentitis. However, the …
A CGA/EGFR/GATA2 positive feedback circuit confers chemoresistance in gastric cancer
T Cao, Y Lu, Q Wang, H Qin, H Li… - The Journal of …, 2022 - Am Soc Clin Investig
De novo and acquired resistance are major impediments to the efficacy of conventional and
targeted cancer therapy. In unselected gastric cancer (GC) patients with advanced disease …
targeted cancer therapy. In unselected gastric cancer (GC) patients with advanced disease …
Human chorionic gonadotrophin: new pleiotropic functions for an “old” hormone during pregnancy
V Gridelet, S Perrier d'Hauterive, B Polese… - Frontiers in …, 2020 - frontiersin.org
Human chorionic gonadotrophin (hCG) is the first specific molecule synthesized by the
embryo. hCG RNA is transcribed as early as the eight-cell stage, and the blastocyst …
embryo. hCG RNA is transcribed as early as the eight-cell stage, and the blastocyst …
Iodine and thyroid maternal and fetal metabolism during pregnancy
C Mégier, G Dumery, D Luton - Metabolites, 2023 - mdpi.com
Thyroid hormones and iodine are required to increase basal metabolic rate and to regulate
protein synthesis, long bone growth and neuronal maturation. They are also essential for …
protein synthesis, long bone growth and neuronal maturation. They are also essential for …
Mechanisms for establishment of the placental glucocorticoid barrier, a guard for life
The fetus is shielded from the adverse effects of excessive maternal glucocorticoids by 11β-
HSD2, an enzyme which is expressed in the syncytial layer of the placental villi and is …
HSD2, an enzyme which is expressed in the syncytial layer of the placental villi and is …
Engineering placenta‐like organoids containing endogenous vascular cells from human‐induced pluripotent stem cells
The placenta is an essential organ that maintains the health of both the fetus and its mother.
Understanding the development of human placenta has been hindered by the limitations of …
Understanding the development of human placenta has been hindered by the limitations of …
Generation of a highly biomimetic organoid, including vasculature, resembling the native immature testis tissue
The creation of a testis organoid (artificial testis tissue) with sufficient resemblance to the
complex form and function of the innate testis remains challenging, especially using non …
complex form and function of the innate testis remains challenging, especially using non …
[HTML][HTML] Immune-related mechanisms and immunotherapy in extragonadal germ cell tumors
W Xiu, J Pang, Y Hu, H Shi - Frontiers in Immunology, 2023 - frontiersin.org
Purpose of review Extragonadal germ cell tumors (EGCTs) are relatively rare tumors,
accounting for 1%–5% of all GCTs. In this review, we summarize the current research …
accounting for 1%–5% of all GCTs. In this review, we summarize the current research …