Hepatitis C virus infection in children and adolescents

G Indolfi, P Easterbrook, G Dusheiko… - The lancet …, 2019 - thelancet.com
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and associated
morbidity and mortality worldwide. Short-course, oral, curative, direct-acting antiviral …

Systematic review with meta‐analysis: the efficacy and safety of direct‐acting antivirals in children and adolescents with chronic hepatitis C virus infection

G Indolfi, S Giometto, D Serranti… - Alimentary …, 2020 - Wiley Online Library
Background The effect of direct‐acting anti‐virals (DAAs) in children and adolescents with
chronic hepatitis C virus (HCV) infection is difficult to determine, since few, aged between 3 …

Hepatitis C virus infection in children: How do we prevent it and how do we treat it?

A Nwaohiri, S Schillie, M Bulterys… - Expert review of anti …, 2018 - Taylor & Francis
ABSTRACT Introduction: Hepatitis C virus (HCV) infection is an important contributor to the
worldwide burden of liver-related morbidity and mortality. Mother-to-child transmission of …

Efficacy and safety of DAA in children and adolescents with chronic HCV infection: a systematic review and meta‐analysis

G Indolfi, P Easterbrook, S Giometto, F Malik… - Liver …, 2024 - Wiley Online Library
Abstract Background and Aims We evaluated the effectiveness and safety of pan‐genotypic
regimens, glecaprevir/pibrentasvir (GLE/PIB), sofosbuvir/velpatasvir (SOF/VEL), and …

Hepatitis C virus treatment in children: a challenge for hepatitis C virus elimination

MH El-Sayed, G Indolfi - Seminars in Liver Disease, 2020 - thieme-connect.com
Hepatitis C is a global public health threat. The introduction of direct-acting antivirals (DAAs)
brings the prospect of curing the 71 million people living with the disease, dramatically …

[HTML][HTML] Cascade of care for children and adolescents with chronic hepatitis C

ME Rogers, WF Balistreri - World Journal of Gastroenterology, 2021 - ncbi.nlm.nih.gov
Chronic hepatitis C virus (HCV) infection presents a significant global public health burden.
In 2015, over 400000 deaths worldwide were attributed to HCV infection. This led the World …

[PDF][PDF] Perinatal transmission of hepatitis C virus: an update

MHF El-Shabrawi, NM Kamal, EA Mogahed… - Archives of medical …, 2020 - termedia.pl
Infection with hepatitis C virus (HCV) is a major health problem worldwide. A large
proportion of perinatal HCV infections are silent and may present later in adulthood with …

Generic sofosbuvir/ledipasvir for the treatment of genotype 4 chronic hepatitis C in Egyptian children (9–12 years) and adolescents

HA El-Araby, BE Behairy, MA El-Guindi… - Hepatology …, 2019 - Springer
Background/purpose of the study Worldwide and national efforts are directed against
eradication of HCV. The introduction of direct-acting antivirals (DAAs) has changed …

Effects of sofosbuvir/ledipasvir therapy on chronic hepatitis C virus genotype 4, infected children of 3‐6 years of age

EM Kamal, M El‐Shabrawi, H El‐Khayat… - Liver …, 2020 - Wiley Online Library
Abstract Background & Aims Treatment of children aged 3‐6 genotype 4 is still limited by the
interferon side effects. We aimed in this study to evaluate the effectiveness and safety of …

Safety and EFFICACY of 8 weeks Ledipasvir/Sofosbuvir for chronic hepatitis C genotype 4 in children aged 4-10 years

BE Behairy, HA El-Araby, MA El-Guindi… - The Journal of …, 2020 - Elsevier
Objective To evaluate the safety and efficacy of shortened 8-week regimen of
ledipasvir/sofosbuvir (LED/SOF) combination therapy in treatment-naïve children without …