Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

Abstract Peroxiredoxins (Prx), thiol-dependent peroxidases, were first identified as H 2 O 2
detoxifiers, and more recently as H 2 O 2 sensors, intermediates in redox-signaling …

Peroxiredoxins (Prdxs) sense and assess peroxide levels, and signal through protein
interactions. Understanding the role of the multiple structural and post-translational …

Disulfide bond formation is fundamentally important for protein structure and constitutes a
key mechanism by which cells regulate the intracellular oxidation state. Peroxiredoxins …

One of the major challenges that remain in the fields of aging and lifespan determination
concerns the precise roles that reactive oxygen species (ROS) play in these processes …

Peroxiredoxin 2 (Prdx2) is the third most abundant erythrocyte protein. It was known
previously as calpromotin since its binding to the membrane stimulates the calcium …

The study of metabolism is undergoing a renaissance. Since the year 2002, over 50
genetically-encoded fluorescent indicators (GEFIs) have been introduced, capable of …

Peroxiredoxins play central roles in the detoxification of reactive oxygen species and have
been modelled across multiple organisms using a variety of kinetic methods. However, the …

Enhanced production of reactive oxygen species (ROS) triggered by various stimuli,
including viral infections, has attributed much attention in the past years. It has been shown …

Peroxiredoxins (PRDXs) are abundant peroxidases present in all kingdoms of life. Recently,
they have been shown to also carry out additional roles as molecular chaperones. To …