Conditioned place preference (CPP) continues to be one of the most popular models to
study the motivational effects of drugs and non‐drug treatments in experimental animals …

Despite the high prevalence of neuropsychiatric disorders, their aetiology and molecular
mechanisms remain poorly understood. The zebrafish (Danio rerio) is increasingly utilized …

The reinforcing (rewarding) effects of psychomotor stimulants (cocaine and amphetamine)
depend on the mesocorticolimbic dopamine system innervating the nucleus accumbens …

The prefrontal cortex (PFC) has long been known to be involved in the mediation of complex
behavioral responses. Considerable research efforts are directed towards refining the …

The involvement of the hippocampus and the prefrontal cortex in cognitive processes and
particularly in learning and memory has been known for a long time. However, the specific …

Although some studies report increased responsiveness of nucleus accumbens (NAc)
AMPA receptors (AMPARs) after withdrawal from repeated cocaine treatment, others report …

The amygdala is a heterogeneous brain structure implicated in processing of emotions and
storing the emotional aspects of memories. Gene activity markers such as c-Fos have been …

The brain reward circuitry plays a key role in emotional and motivational behaviors, and its
dysfunction underlies neuropsychiatric disorders such as schizophrenia, depression and …

To study the role of glutamate in cocaine‐conditioned responses, we developed a rat model
in which conditioned locomotion is produced by repeated pairing of cocaine with discrete …

The present paper proposes a model for the identification and the validation of brain
processes and mechanisms underlying smokers' cue reactivity. Smoking behaviour is …