Doxorubicin—an agent with multiple mechanisms of anticancer activity
Doxorubicin (DOX) constitutes the major constituent of anti-cancer treatment regimens
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
[HTML][HTML] Polychemotherapy with curcumin and doxorubicin via biological nanoplatforms: enhancing antitumor activity
M Ashrafizadeh, A Zarrabi, F Hashemi, A Zabolian… - Pharmaceutics, 2020 - mdpi.com
Doxorubicin (DOX) is a well-known chemotherapeutic agent extensively applied in the field
of cancer therapy. However, similar to other chemotherapeutic agents such as cisplatin …
of cancer therapy. However, similar to other chemotherapeutic agents such as cisplatin …
Protective effects of chrysin against oxidative stress and inflammation induced by lead acetate in rat kidneys: a biochemical and histopathological approach
In this study, the protective effects of chrysin (CR) on lead acetate (PbAc)-induced renal
toxicity in Sprague-Dawley rats were investigated with biochemical, histopathological, and …
toxicity in Sprague-Dawley rats were investigated with biochemical, histopathological, and …
Hesperidin protects against the chlorpyrifos‐induced chronic hepato‐renal toxicity in rats associated with oxidative stress, inflammation, apoptosis, autophagy, and up …
In this study, we investigated the effects of hesperidin (HSP) on oxidants/antioxidants status,
inflammation, apoptotic, and autophagic activity in hepato‐renal toxicity induced by chronic …
inflammation, apoptotic, and autophagic activity in hepato‐renal toxicity induced by chronic …
Evaluation of protective effects of quercetin against cypermethrin‐induced lung toxicity in rats via oxidative stress, inflammation, apoptosis, autophagy, and …
M Ileriturk, O Kandemir… - Environmental …, 2022 - Wiley Online Library
Cypermethrin (CYP), a type II synthetic pyrethroid, is the most widely used insecticide
worldwide. Inhalation of it may cause side effects. This study is aimed to examine potential …
worldwide. Inhalation of it may cause side effects. This study is aimed to examine potential …
Rutin ameliorates mercuric chloride-induced hepatotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis
Objective Mercury is a global environmental pollutant and is responsible for several organ
pathophysiology including oxidative stress-induced liver disorders. Therefore, the present …
pathophysiology including oxidative stress-induced liver disorders. Therefore, the present …
Naringin protects against cyclophosphamide-induced hepatotoxicity and nephrotoxicity through modulation of oxidative stress, inflammation, apoptosis, autophagy …
Cyclophosphamide (CP) is a common chemotherapeutic agent that is effective against a
wide variety of tumors. The associated hepatotoxicity and nephrotoxicity, however, limit its …
wide variety of tumors. The associated hepatotoxicity and nephrotoxicity, however, limit its …
Protective effect of chrysin on cyclophosphamide-induced hepatotoxicity and nephrotoxicity via the inhibition of oxidative stress, inflammation, and apoptosis
Cyclophosphamide (CYP) is a chemotherapeutic agent used in the treatment of autoimmune
disorders and malignant diseases. However, its usage is restricted due to its severe side …
disorders and malignant diseases. However, its usage is restricted due to its severe side …
Quercetin provides protection against the peripheral nerve damage caused by vincristine in rats by suppressing caspase 3, NF-κB, ATF-6 pathways and activating …
In the present study, the protective effects of quercetin on peripheral neurotoxicity caused by
vincristine, which is used effectively in the treatment of various types of cancers, were …
vincristine, which is used effectively in the treatment of various types of cancers, were …
Neuroprotective effect of rutin against colistin-induced oxidative stress, inflammation and apoptosis in rat brain associated with the CREB/BDNF expressions
The purpose of the current study was to examine the neuroprotective effect of rutin against
colistin-induced neurotoxicity in rats. Thirty-five male Sprague Dawley rats were randomly …
colistin-induced neurotoxicity in rats. Thirty-five male Sprague Dawley rats were randomly …