Mitochondrial dysfunction and chronic inflammation in polycystic ovary syndrome

SA Dabravolski, NG Nikiforov, AH Eid… - International journal of …, 2021 - mdpi.com
Polycystic ovarian syndrome (PCOS) is the most common endocrine–metabolic disorder
affecting a vast population worldwide; it is linked with anovulation, mitochondrial …

The role of androgen and its related signals in PCOS

W Ye, T Xie, Y Song, L Zhou - Journal of cellular and molecular …, 2021 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women at
reproductive age. However, the underlying pathogenic mechanisms have not been …

Mechanisms of and potential medications for oxidative stress in ovarian granulosa cells: a review

S Liu, Y Jia, S Meng, Y Luo, Q Yang, Z Pan - International Journal of …, 2023 - mdpi.com
Granulosa cells are essential for follicle initiation and development, and their abnormal
function or apoptosis is a crucial factor leading to follicular atresia. A state of oxidative stress …

Oxidative stress and mitochondrial dysfunction of granulosa cells in polycystic ovarian syndrome

Y Gao, Y Zou, G Wu, L Zheng - Frontiers in Medicine, 2023 - frontiersin.org
Polycystic ovarian syndrome (PCOS) is one of the leading causes of anovulatory infertility in
women, affecting 5%–15% of women of reproductive age worldwide. The clinical …

The role of vitamin D on redox regulation and cellular senescence

E Sosa-Díaz, EY Hernández-Cruz… - Free Radical Biology …, 2022 - Elsevier
Vitamin D is considered an essential micronutrient for human health that is metabolized into
a multifunctional secosteroid hormone. We can synthesize it in the skin through ultraviolet B …

β-Sitosterol ameliorates endometrium receptivity in PCOS-like mice: the mediation of gut microbiota

Y Yu, Y Cao, W Huang, Y Liu, Y Lu, J Zhao - Frontiers in Nutrition, 2021 - frontiersin.org
Background: Polycystic ovary syndrome (PCOS), one of the most common endocrine
diseases in women of childbearing age, has been found to be accompanied by changes in …

The role of peroxisome proliferator-activated receptors in polycystic ovary syndrome

I Psilopatis, K Vrettou, E Nousiopoulou… - Journal of Clinical …, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) constitutes the most common endocrine disorder in
women of reproductive age. Patients usually suffer from severe menstrual irregularities, skin …

Rat BAT xenotransplantation recovers the fertility and metabolic health of PCOS mice

L Du, Y Wang, CR Li, LJ Chen, JY Cai… - Journal of …, 2021 - joe.bioscientifica.com
Polycystic ovarian syndrome (PCOS) is a major severe ovary disorder affecting 5–10% of
reproductive women around the world. PCOS can be considered a metabolic disease …

Seasonal changes of vitamin D3 and ovarian steroidogenesis in the wild ground squirrels (Citellus dauricus Brandt)

W Lu, Y Zhou, Y Liu, H Zhang, Z Yuan, Y Han… - The Journal of Steroid …, 2023 - Elsevier
There is mounting evidence that vitamin D 3 regulates female reproductive function critically,
while little is known about the function of seasonally variable vitamin D 3 in regulating …

Vitamin D in follicular development and oocyte maturation

F Xu, S Wolf, J Xu - Reproduction, 2021 - rep.bioscientifica.com
Vitamin D (VD) is a secosteroid hormone synthesized predominantly in the skin upon
ultraviolet light exposure, which can also be obtained from dietary sources. In target cells …