Alteration in the expression of cell-surface proteins is a common consequence of malignant
transformation. Natural killer (NK) cells use an array of germline-encoded activating and …

The ability of tumors to manage an immune‐mediated attack has been recently included in
the “next generation” of cancer hallmarks. In solid tumors, the microenvironment that is …

Immune cells infiltrating tumors can have important impact on tumor progression and
response to therapy. We present an efficient algorithm to simultaneously estimate the …

Objective: Exosomes are nanovesicles that are released from normal and tumor cells and
are detectable in cell culture supernatant and human biological fluids. Although previous …

Purpose: Natural killer (NK) cells play a critical role in tumor immunosurveillance. Multiple
activating and inhibitory receptors (IR) regulate NK-cell–mediated tumor control. The IR T …

Antibody-dependent cellular cytotoxicity (ADCC) is exerted by immune cells expressing
surface Fcγ receptors (FcγRs) against cells coated with antibody, such as virus-infected or …

While blocking tumor growth by targeting autophagy is well established, its role on the
infiltration of natural killer (NK) cells into tumors remains unknown. Here, we investigate the …

Purpose: Tumor infiltration by different T lymphocyte subsets is known to be associated with
favorable prognosis in colorectal cancer. Still debated is the role of innate immune system …

Natural killer cells are powerful effectors of innate immunity that constitute a first line of
defense against cancer. NK cells express an array of germline-encoded receptors which …

Endometrial Cancer is the most common cancer in the female genital tract in developed
countries, and with its increasing incidence due to risk factors such as aging and obesity …