Regulatory B cells (Bregs) is a term that encompasses all B cells that act to suppress
immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing …

Understanding nephron loss is a primary strategy for preventing CKD progression. Death of
renal tubular cells may occur by apoptosis during developmental and regenerative …

Abstract Background Regulatory B (Breg) cells represent one of the B cell subsets that
infiltrate solid tumors and exhibit distinct phenotypes in different tumor microenvironments …

Abstract Kidney injury molecule 1 (KIM-1) is a type I membrane protein, comprising an
extracellular portion and a cytoplasmic portion. It is also named as HAVCR1 (Hepatitis A …

The TIM (T cell/transmembrane, immunoglobulin, and mucin) gene family plays a critical role
in regulating immune responses, including allergy, asthma, transplant tolerance …

Flaviviruses enter host cells by endocytosis initiated when the virus particles interact with
cell surface receptors. The current model suggests that flaviviruses use at least two different …

In programmed cell death, a large number of cells undergo apoptosis, and are engulfed by
macrophages to avoid the release of noxious materials from the dying cells,. In definitive …

To maintain organismal homeostasis, phagocytes engulf dead cells, which are recognized
as dead by virtue of a characteristic" eat me" signal exposed on their surface. The dead cells …

Human T-cell Immunoglobulin and Mucin-domain containing proteins (TIM1, 3, and 4)
specifically bind phosphatidylserine (PS). TIM1 has been proposed to serve as a cellular …

T cell Ig domain and mucin domain protein 1 (TIM-1) is a costimulatory molecule that
regulates immune responses by modulating CD4+ T cell effector differentiation. However …