Nanotechnological approaches in prostate cancer therapy: integration of engineering and biology

M Ashrafizadeh, S Aghamiri, SC Tan, A Zarrabi… - Nano Today, 2022 - Elsevier
Nanocarriers have received special attention in biomedicine for the treatment of various
diseases, especially cancer, as one of the leading causes of death worldwide. Nanocarriers …

[HTML][HTML] Liposome-based diagnostic and therapeutic applications for pancreatic cancer

F Raza, L Evans, M Motallebi, H Zafar, M Pereira-Silva… - Acta Biomaterialia, 2023 - Elsevier
Pancreatic cancer is one of the harshest and most challenging cancers to treat, often labeled
as incurable. Chemotherapy continues to be the most popular treatment yet yields a very …

[HTML][HTML] Gene regulation by antisense transcription: A focus on neurological and cancer diseases

S Najafi, SC Tan, P Raee, Y Rahmati… - Biomedicine & …, 2022 - Elsevier
Advances in high-throughput sequencing over the past decades have led to the
identification of thousands of non-coding RNAs (ncRNAs), which play a major role in …

Recent advances in codelivery of curcumin and siRNA as anticancer therapeutics

M Sanati, AR Afshari, P Kesharwani… - European Polymer …, 2023 - Elsevier
Addressing the need for effective cancer chemotherapy with low adverse effects has been
partially possible through innovative therapeutic approaches combining chemotherapeutics …

Targeted nanodelivery of siRNA against KRAS G12D inhibits pancreatic cancer

R Huang, H Du, L Cheng, P Zhang, F Meng, Z Zhong - Acta Biomaterialia, 2023 - Elsevier
Pancreatic cancer (PC) stands as a most deadly malignancy due to few effective treatments
in the clinics. KRAS G12D mutation is a major driver for most PC cases, and silencing of …

[HTML][HTML] Nano-drug delivery system for pancreatic cancer: A visualization and bibliometric analysis

JF Zhao, FL Zou, JF Zhu, C Huang, FQ Bu… - Frontiers in …, 2022 - frontiersin.org
Background: Nano drug delivery system (NDDS) can significantly improve the delivery and
efficacy of drugs against pancreatic cancer (PC) in many ways. The purpose of this study is …

[HTML][HTML] Nanocarriers for delivery of siRNA as gene silencing mediator

A Morales-Becerril, L Aranda-Lara, K Isaac-Olivé… - EXCLI …, 2022 - ncbi.nlm.nih.gov
The term nanocarrier refers to sub-micrometric particles of less than 100 nm, designed to
transport, distribute, and release nanotechnology-based drug delivery systems. siRNA …

Bioengineered protein nanocage by small heat shock proteins delivering mTERT siRNA for enhanced colorectal cancer suppression

H Wang, N Liu, F Yang, N Hu, M Wang… - ACS Applied Bio …, 2022 - ACS Publications
The efficient delivery of small interfering RNA (siRNA) for target gene silencing holds great
promise for cancer therapy. Protein nanocages have attracted considerable attention as …

[HTML][HTML] Autophagy, a critical element in the aging male reproductive disorders and prostate cancer: a therapeutic point of view

P Raee, SC Tan, S Najafi, F Zandsalimi, TY Low… - Reproductive Biology …, 2023 - Springer
Autophagy is a highly conserved, lysosome-dependent biological mechanism involved in
the degradation and recycling of cellular components. There is growing evidence that …

A systems biology approach and in vitro experiment indicated Rapamycin targets key cancer and cell cycle‐related genes and miRNAs in triple‐negative breast …

A Tafti, S Shojaei, H Zali, S Karima… - Molecular …, 2023 - Wiley Online Library
An anticancer drug known as Rapamycin acts by inhibiting the mammalian target of the
Rapamycin pathway. This agent has recently been investigated for its potential therapeutic …