Acute rheumatic fever (ARF) is the result of an autoimmune response to pharyngitis caused
by infection with group A Streptococcus. The long-term damage to cardiac valves caused by …

Rheumatic heart disease (RHD) is a major cause of cardiovascular morbidity and mortality
in low-and middle-income countries, where living conditions promote spread of group A β …

Canine myxomatous mitral valve disease (MMVD) is similar to Barlow's form of MMVD in
humans. These valvulopathies are complex, with varying speeds of progression. We …

Introduction Rheumatic heart disease (RHD), degenerative aortic stenosis (AS), and
congenital valve diseases are prevalent in sub-Saharan Africa. Many knowledge gaps …

Background Myxomatous mitral valve disease (MVD) is the most common acquired heart
disease in dogs, and the Cavalier King Charles Spaniel (CKCS) is the most studied breed …

Autoimmune inflammatory reactions leading to rheumatic fever (RF) and rheumatic heart
disease (RHD) result from untreated Streptococcus pyogenes throat infections in individuals …

Rheumatic fever (RF) and rheumatic heart disease (RHD) follow untreated S. pyogenes
throat infections in children who present susceptible genes that favor the development of …

Rheumatic heart disease (RHD) is an autoimmune sequel of pharyngitis and rheumatic
fever that leads to permanent heart valve damage, especially the mitral valves. The mitral …

Septin genes were originally identified in budding yeast in 1971. Since their original
discovery, at least 13 mammalian genes have now been found, which give rise to a vast …

Fundamentos: Os mecanismos subjacentes pelos quais a doença cardíaca reumática
(DCR) levam à disfunção valvar grave não são totalmente compreendidos. Objetivo: O …