[HTML][HTML] An Update on the Clinical Pipelines of New Antibacterial Drugs Developed in China

X Yang, C Li, X Wang, Z Zheng, P Sun, C Xu, L Chen… - Engineering, 2024 - Elsevier
Antibacterial resistance is a global health threat that requires further concrete action on the
part of all countries. In this context, one of the biggest concerns is whether enough new …

Design, Synthesis, and Biological Evaluation of Novel Arylomycins against Multidrug-Resistant Gram-Negative Bacteria

Y Zhang, D Zhang, W Zhao, H Li, Z Lu… - Journal of Medicinal …, 2024 - ACS Publications
G0775, an arylomycin-type SPase I inhibitor that is being evaluated in a preclinical study,
exhibited potent antibacterial activities against some Gram-negative bacteria but meanwhile …

Library screening for synergistic combinations of FDA-approved drugs and metabolites with vancomycin against Vana-type vancomycin-resistant Enterococcus …

S Gargvanshi, WG Gutheil - Microbiology Spectrum, 2022 - Am Soc Microbiol
Antimicrobial resistance is a major public health threat, and there is an urgent need for new
strategies to address this issue. In a recent study, a library screening strategy was …

[HTML][HTML] Hypoxia Increases the Tempo of Phage Resistance and Mutational Bottlenecking of Pseudomonas aeruginosa

AR Schumann, AD Sue, DR Roach - Frontiers in Microbiology, 2022 - frontiersin.org
Viruses that infect bacteria (ie, phages) are abundant and widespread in the human body,
and new anti-infective approaches such as phage therapy are essential for the future of …

[HTML][HTML] Use of Aloe Vera Gel as Media to Assess Antimicrobial Activity and Development of Antimicrobial Nanocomposites

E Rauwel, G Arya, K Praakle, P Rauwel - International Journal of …, 2024 - mdpi.com
Antimicrobial resistance is a menace to public health on a global scale. In this regard,
nanomaterials exhibiting antimicrobial properties represent a promising solution. Both metal …

Ultrasound-active ReCORM-AIEgen for gas and sonodynamic therapy of mycobacterium biofilms

Y Li, H Wang, Q Lin, X Yu, H Huang, P Zhang - Science China Chemistry, 2023 - Springer
Bacterial infection is the leading cause of many severe inflammation diseases. The
development of novel and effective therapeutic approaches to counter bacterial infections …

Aminoquinoline-triazine Conjugates: Design, Synthesis, Antibacterial Activity, and SAR Analysis

SH Ansari, S Sahu, A Shakya, SK Ghosh… - Letters in Drug …, 2023 - ingentaconnect.com
Aim: Frequent use of antibiotics is responsible for the development of antibiotic resistance;
thus, there is an urgent need for the development of new antibacterial agents that act by …

Maternal knowledge and prescribing practices of antibiotics for childhood infections: a cross-sectional survey in Jordan

R Abdeljawad, O Abu-Hammad… - Healthcare in Low …, 2023 - pagepressjournals.org
This article aims to assess the knowledge and practices of Jordanian mothers regarding
antibiotic consumption by their children. A questionnaire was distributed to mothers during …

[图书][B] Library Screening and Focused Multiomics of Antibacterial Action on Vamcomycin-Resistant Enterococcus faecium

S Gargvanshi - 2023 - search.proquest.com
Antimicrobial resistance is a major public health threat, and there is an urgent need for new
strategies to address this issue. In a gram-positive bacteria, the peptidoglycan layer is thick …