Imaging calcium in neurons
C Grienberger, A Konnerth - Neuron, 2012 - cell.com
Calcium ions generate versatile intracellular signals that control key functions in all types of
neurons. Imaging calcium in neurons is particularly important because calcium signals exert …
neurons. Imaging calcium in neurons is particularly important because calcium signals exert …
NMDA receptor-dependent long-term potentiation and long-term depression (LTP/LTD)
C Lüscher, RC Malenka - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
Long-term potentiation and long-term depression (LTP/LTD) can be elicited by activating N-
methyl-d-aspartate (NMDA)-type glutamate receptors, typically by the coincident activity of …
methyl-d-aspartate (NMDA)-type glutamate receptors, typically by the coincident activity of …
Dendritic spines: the locus of structural and functional plasticity
C Sala, M Segal - Physiological reviews, 2014 - journals.physiology.org
The introduction of high-resolution time lapse imaging and molecular biological tools has
changed dramatically the rate of progress towards the understanding of the complex …
changed dramatically the rate of progress towards the understanding of the complex …
Pyramidal neurons: dendritic structure and synaptic integration
N Spruston - Nature Reviews Neuroscience, 2008 - nature.com
Pyramidal neurons are characterized by their distinct apical and basal dendritic trees and
the pyramidal shape of their soma. They are found in several regions of the CNS and …
the pyramidal shape of their soma. They are found in several regions of the CNS and …
Natural oligomers of the Alzheimer amyloid-β protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway
GM Shankar, BL Bloodgood, M Townsend… - Journal of …, 2007 - Soc Neuroscience
Alzheimer's disease (AD) is characterized by decreased synapse density in hippocampus
and neocortex, and synapse loss is the strongest anatomical correlate of the degree of …
and neocortex, and synapse loss is the strongest anatomical correlate of the degree of …
Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior
DJ Selkoe - Behavioural brain research, 2008 - Elsevier
During the last 25 years, neuropathological, biochemical, genetic, cell biological and even
therapeutic studies in humans have all supported the hypothesis that the gradual cerebral …
therapeutic studies in humans have all supported the hypothesis that the gradual cerebral …
Small-Conductance Ca2+-Activated K+ Channels: Form and Function
JP Adelman, J Maylie, P Sah - Annual review of physiology, 2012 - annualreviews.org
Small-conductance Ca2+-activated K+ channels (SK channels) are widely expressed
throughout the central nervous system. These channels are activated solely by increases in …
throughout the central nervous system. These channels are activated solely by increases in …
Dendritic excitability and synaptic plasticity
Most synaptic inputs are made onto the dendritic tree. Recent work has shown that dendrites
play an active role in transforming synaptic input into neuronal output and in defining the …
play an active role in transforming synaptic input into neuronal output and in defining the …
GluN2A and GluN2B subunit-containing NMDA receptors in hippocampal plasticity
OA Shipton, O Paulsen - Philosophical Transactions of …, 2014 - royalsocietypublishing.org
N-Methyl-d-aspartate receptor (NMDAR)-dependent synaptic plasticity is a strong candidate
to mediate learning and memory processes that require the hippocampus. This plasticity is …
to mediate learning and memory processes that require the hippocampus. This plasticity is …
Increased prevalence of calcium transients across the dendritic arbor during place field formation
MEJ Sheffield, MD Adoff, DA Dombeck - Neuron, 2017 - cell.com
Hippocampal place cell ensembles form a cognitive map of space during exposure to novel
environments. However, surprisingly little evidence exists to support the idea that synaptic …
environments. However, surprisingly little evidence exists to support the idea that synaptic …