Comprehensive review on the positive and negative effects of various important regulators on male spermatogenesis and fertility

HH Chao, Y Zhang, PY Dong, S Gurunathan… - Frontiers in …, 2023 - frontiersin.org
With the increasing global incidence of infertility, the influence of environmental factors,
lifestyle habits, and nutrients on reproductive health has gradually attracted the attention of …

Cardiovascular toxicity induced by chronic vincristine treatment

E Herradón, C González, A González… - Frontiers in …, 2021 - frontiersin.org
Vincristine is an effective anticancer agent for treating leukemias, lymphomas, and other
solid tumors. Vincristine's better-known severe side effects include bone marrow depression …

The Hepatoprotective Possessions of Specific Iranian Medicinal Plants

S Dini, S Singh, F Fatemi - Journal of Food Biochemistry, 2024 - Wiley Online Library
With its historical roots, Iranian traditional medicine has played a significant role in
addressing liver‐related disorders and providing alternative approaches to synthetic drugs …

Synchrotron Radiation FTIR Microspectroscopy Study of Biomolecular Alterations in Vincristine-Treated WRL68 Cells at the Single-Cell Level

J Zhong, W Yu, Y Tang, X Zhou - ACS omega, 2022 - ACS Publications
The toxic effect of vincristine on hepatocytes has rarely been studied. Synchrotron radiation-
based Fourier transform infrared (SR-FTIR) microspectroscopy is a novel technique for …

[HTML][HTML] Crocin promotes apoptosis in human EBV-transformed B-lymphocyte via intrinsic pathway

AS Jahromi, M Kargar, F Kafilzadeh… - … of Hematology and …, 2021 - ncbi.nlm.nih.gov
Background As a major carotenoid in saffron, crocin demonstrates potent anti-cancer
impacts. However, its anti-lymphoma effects remain vague, especially in the human EBV …

Antioxidant-Based Preventive Effect of Phytochemicals on Anticancer Drug-Induced Hepatotoxicity

JE Park, CH Ahn, HJ Lee, DY Sim, SY Park… - Antioxidants & Redox …, 2023 - liebertpub.com
Significance: Drug-induced liver injury (DILI) or hepatotoxicity has been a hot issue to
overcome on the safety and physiological function of the liver, since it is known to have …

[PDF][PDF] Saffron (Crocus sativus L.) based protection against Aflatoxin B1 induced haematological and organ damages in rats

H Ashi, EA Hamed, B Refaat, S Idris… - Acta Biologica …, 2024 - journals.uni-lj.si
Saffron is well-known for its anti-apoptotic, anti-inflammatory, and antioxidant properties.
Saffron's nutritional and medicinal properties support its numerous uses as a flavouring and …

Chemotherapy-Induced Liver Injury: Unveiling Emerging Mechanisms and Exploring Mitigation Strategies

MA Alkabbani, AAS Shatat, AN Ghazy… - ERU Research …, 2024 - erurj.journals.ekb.eg
In this comprehensive overview of chemotherapy-induced liver injury, various classes of
chemotherapeutic agents were reviewed to elucidate the complex cellular events …

Gallic Acid Attenuates Cardiovascular and Hematological Complications in Vincristine Treatment via Hydroxyl Radical Scavenging and Endogenous Antioxidant …

OI Azeez, AA Oyagbemi… - European Journal of …, 2023 - ej-med.org.ejece.org
The menace of cancer and the nightmare of complications of cancer chemotherapy have
driven researchers to explore simple but efficient combination therapy that includes …

Study the Possible Protective Effect of Saffron Extract on Induced Rats Toxicity by Acrylamide

M Omar, S Mahmoud - Egyptian Journal of Nutrition and …, 2022 - ejnh.journals.ekb.eg
Acrylamide is a dietary pollutant in a variety of commonly eaten food product, and been
attributed to liver and kidney damage. Some researchers suggest that saffron, and its active …