Epigenetic age prediction

DJ Simpson, T Chandra - Aging cell, 2021 - Wiley Online Library
Advanced age is the main common risk factor for cancer, cardiovascular disease and
neurodegeneration. Yet, more is known about the molecular basis of any of these groups of …

Attachment across the lifespan: examining the intersection of pair bonding neurobiology and healthy aging

KM Berendzen, KL Bales, DS Manoli - Neuroscience & Biobehavioral …, 2023 - Elsevier
Increasing evidence suggests that intact social bonds are protective against age-related
morbidity, while bond disruption and social isolation increase the risk for multiple age …

Development of epigenetic clocks for key ruminant species

A Caulton, KG Dodds, KM McRae, C Couldrey… - Genes, 2021 - mdpi.com
Robust biomarkers of chronological age have been developed in humans and model
mammalian species such as rats and mice using DNA methylation data. The concept of …

DNA methylation networks underlying mammalian traits

A Haghani, CZ Li, TR Robeck, J Zhang, AT Lu… - Science, 2023 - science.org
Using DNA methylation profiles (n= 15,456) from 348 mammalian species, we constructed
phyloepigenetic trees that bear marked similarities to traditional phylogenetic ones. Using …

Divergent age-related methylation patterns in long and short-lived mammals

A Haghani, N Wang, AT Lu, K Mozhui… - BioRxiv, 2022 - biorxiv.org
Age-related changes to cytosine methylation have been extensively characterized across
the mammalian family. Some cytosines that are conserved across mammals exhibit age …

Transcription and DNA methylation signatures of paternal behavior in hippocampal dentate gyrus of prairie voles

NJ Waddell, Y Liu, JM Chitaman, GJ Kaplan, Z Wang… - Scientific Reports, 2023 - nature.com
In socially monogamous prairie voles (Microtus ochrogaster), parental behaviors not only
occur in mothers and fathers, but also exist in some virgin males. In contrast, the other virgin …

Development of epigenetic clocks for New Zealand livestock

A Caulton, KG Dodds, KM McRae, C Couldrey… - bioRxiv, 2021 - biorxiv.org
Robust biological biomarkers of chronological age have been developed in humans and
model mammalian species such as rats and mice using DNA methylation data. The concept …