A3 Coupling Reaction in the Synthesis of Heterocyclic Compounds

Y Volkova, S Baranin, I Zavarzin - Advanced Synthesis & …, 2021 - Wiley Online Library
In recent years, the transition‐metal catalyzed three‐component coupling of an aldehyde, an
alkyne and an amine, commonly called A3 coupling has become a powerful tool in organic …

Recent Advances in the A3 Coupling Reactions and their Applications

I Jesin, GC Nandi - European Journal of Organic Chemistry, 2019 - Wiley Online Library
Propargylamines are an important class of organic compounds that have been widely used
as building blocks for the synthesis of various kinds of chemically and biologically relevant …

Flow synthesis approaches to privileged scaffolds–recent routes reviewed for green and sustainable aspects

AI Alfano, M Brindisi, H Lange - Green Chemistry, 2021 - pubs.rsc.org
Privileged scaffolds as starting points toward biologically active molecules represent a
neuralgic point in drug discovery. The ability of synthetic chemists concerned with their …

Recent Advances in Domino Synthesis of Fused Polycyclic N‐Heterocycles Based on Intramolecular Alkyne Hydroamination under Copper Catalysis

Z Jin, G Shen, X Lv - Chinese Journal of Chemistry, 2023 - Wiley Online Library
Comprehensive Summary Fused polycyclic N‐heterocycles are very important scaffolds in
biomedicinal chemistry and materials science. Intramolecular alkyne hydroamination is a …

[HTML][HTML] α-Aminoazoles/azines: key reaction partners for multicomponent reactions

S Imtiaz, S Banoo - RSC advances, 2021 - pubs.rsc.org
Aromatic α-aminoazaheterocycles are the focus of significant investigations and exploration
by researchers owing to their key role in diverse biological and physiological processes. The …

Contemporary progress in the synthetic strategies of imidazole and its biological activities

J Soni, A Sethiya, N Sahiba, DK Agarwal… - Current Organic …, 2019 - ingentaconnect.com
Heterocyclic compounds are pervasive in many areas of life and one of the heterocycles,
imidazole is a unique heterocyclic five-membered aromatic compound having two sp2 …

Diverse synthesis of pyrimido [1, 2-a] benzimidazoles and imidazo [2, 1-b] benzothiazoles via CuI-catalyzed decarboxylic multicomponent reactions of heterocyclic …

J Wu, H Luo, T Wang, H Sun, Q Zhang, Y Chai - Tetrahedron, 2019 - Elsevier
We have developed a straightforward approach to diverse synthesis of 2, 3-, 2, 4-
disubstituted pyrimido [1, 2-a] benzimidazoles, 2, 4, 10-trisubstituted 2, 10-dihydropyrimido …

I 2/DMSO mediated multicomponent reaction for the synthesis of 2-arylbenzo [d] imidazo [2, 1-b] thiazole derivatives

A Jana, P Bhaumick, AK Panday, R Mishra… - Organic & …, 2019 - pubs.rsc.org
Synthesis of a series of 2-arylbenzo [d] imidazo [2, 1-b] thiazoles tethered with barbituric acid
moiety has been reported from the three component reaction of 2-aminobenzothiazoles …

A new fluorescent probe based on imidazole [2, 1-b] benzothiazole for sensitive and selective detection of Cu2+

H Wang, S Zhao, Y Xu, L Li, B Li, M Pei… - Journal of Molecular …, 2020 - Elsevier
A simple fluorescent chemosensor WS1 (N'-[(Z)-1H-indazol-3-ylmethylidene] imidazo [2, 1-
b][1, 3] benzothiazole-2-carbohydrazide) based on imidazole [2, 1-b] benzothiazole was …

Organocatalytic Synthesis of gem‐Difluorinated C2‐Spiro Indolines and Pyrimido[1,2‐a]benzimidazoles from 2‐Alkynyl‐3,3‐Difluoro‐3H‐Indoles

XY Mao, XT Lin, M Yang, GS Chen… - Advanced Synthesis & …, 2018 - Wiley Online Library
In this communication, we report a substrate‐controlled product diversity in the 1, 5, 7‐
triazabicyclo [4.4. 0] dec‐5‐ene (TBD)‐catalyzed cascade cyclization of 2‐alkynyl‐3, 3 …