Competitive endogenous network of circRNA, lncRNA, and miRNA in osteosarcoma chemoresistance
S Qin, Y Wang, C Ma, Q Lv - European Journal of Medical Research, 2023 - Springer
Osteosarcoma is the most prevalent and fatal type of bone tumor. Despite advancements in
the treatment of other cancers, overall survival rates for patients with osteosarcoma have …
the treatment of other cancers, overall survival rates for patients with osteosarcoma have …
Predictors and modulators of synthetic lethality: an update on PARP inhibitors and personalized medicine
S Murata, C Zhang, N Finch, K Zhang… - BioMed research …, 2016 - Wiley Online Library
Poly (ADP‐ribose) polymerase (PARP) inhibitors have proven to be successful agents in
inducing synthetic lethality in several malignancies. Several PARP inhibitors have reached …
inducing synthetic lethality in several malignancies. Several PARP inhibitors have reached …
Significance of BRCA2 and RB1 Co-loss in Aggressive Prostate Cancer Progression
G Chakraborty, J Armenia, YZ Mazzu… - Clinical Cancer …, 2020 - AACR
Purpose: Previous sequencing studies revealed that alterations of genes associated with
DNA damage response (DDR) are enriched in men with metastatic castration-resistant …
DNA damage response (DDR) are enriched in men with metastatic castration-resistant …
Extracellular matrix protein 1 promotes cell metastasis and glucose metabolism by inducing integrin β4/FAK/SOX2/HIF-1α signaling pathway in gastric cancer
L Gan, J Meng, M Xu, M Liu, Y Qi, C Tan, Y Wang… - Oncogene, 2018 - nature.com
Abstract Extracellular matrix protein 1 (ECM1) is related to strong invasiveness and poor
prognosis in major malignancies, but the underlying mechanism remains unknown. Here we …
prognosis in major malignancies, but the underlying mechanism remains unknown. Here we …
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway
S Wang, J Li, J Xie, F Liu, Y Duan, Y Wu, S Huang… - Oncogene, 2018 - nature.com
Although PD-L1 has been shown to play a well-characterized role in inhibiting antitumor
immunity via engagement of its receptor PD-1 in T lymphocytes, little is known about the …
immunity via engagement of its receptor PD-1 in T lymphocytes, little is known about the …
The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer
W Jiang, T He, S Liu, Y Zheng, L Xiang, X Pei… - Journal of hematology & …, 2018 - Springer
Background The study aims to present the effect of PIK3CA E542K and E545K mutations on
glucose metabolism and proliferation and identify their underlying mechanisms in cervical …
glucose metabolism and proliferation and identify their underlying mechanisms in cervical …
Chemotherapy-induced collagen IV drives cancer cell motility through activation of Src and focal adhesion kinase
JP Fatherree, JR Guarin, RA McGinn, SP Naber… - Cancer Research, 2022 - AACR
Triple-negative breast cancer (TNBC) is the most aggressive and deadly subtype of breast
cancer, accounting for 30,000 cases annually in the United States. While there are several …
cancer, accounting for 30,000 cases annually in the United States. While there are several …
Cryptotanshinone suppresses cell proliferation and glucose metabolism via STAT3/SIRT3 signaling pathway in ovarian cancer cells
Y Yang, Y Cao, L Chen, F Liu, Z Qi, X Cheng… - Cancer …, 2018 - Wiley Online Library
Ovarian cancer is the most malignant gynecologic cancer among women worldwide.
Cryptotanshinone (CT), isolated from Salvia miltiorrhiza Bunge, has been identified as a …
Cryptotanshinone (CT), isolated from Salvia miltiorrhiza Bunge, has been identified as a …
A pancancer overview of FBN1, asprosin and its cognate receptor OR4M1 with detailed expression profiling in ovarian cancer
Abstract Ovarian cancer affects> 295,000 women worldwide and is the most lethal of
gynaecological malignancies. Often diagnosed at a late stage, current research efforts seek …
gynaecological malignancies. Often diagnosed at a late stage, current research efforts seek …
Hsa_circ_0004674 promotes osteosarcoma doxorubicin resistance by regulating the miR-342-3p/FBN1 axis
Y Bai, Y Li, J Bai, Y Zhang - Journal of Orthopaedic Surgery and Research, 2021 - Springer
Background The occurrence of chemoresistance is a common problem in tumor treatment.
Circular RNA (circRNA) has been confirmed to be related to tumor chemoresistance …
Circular RNA (circRNA) has been confirmed to be related to tumor chemoresistance …