[HTML][HTML] Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics

U Anand, A Dey, AKS Chandel, R Sanyal, A Mishra… - Genes & …, 2023 - Elsevier
Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and
produce aggressive malignancies that causes millions of deaths every year. With the new …

Mechanism of antimicrobial peptides: antimicrobial, anti-inflammatory and antibiofilm activities

Y Luo, Y Song - International journal of molecular sciences, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are regarded as a new generation of antibiotics. Besides
antimicrobial activity, AMPs also have antibiofilm, immune-regulatory, and other activities …

Intratumoural administration and tumour tissue targeting of cancer immunotherapies

I Melero, E Castanon, M Alvarez, S Champiat… - Nature Reviews …, 2021 - nature.com
Immune-checkpoint inhibitors and chimeric antigen receptor (CAR) T cells are
revolutionizing oncology and haematology practice. With these and other immunotherapies …

Antimicrobial peptides towards clinical application: Delivery and formulation

C Wang, T Hong, P Cui, J Wang, J Xia - Advanced drug delivery reviews, 2021 - Elsevier
Antimicrobial peptides hold promise to supplement small molecules antibiotics and combat
the multidrug resistant microbes. There are however technical hurdles towards the clinical …

Nanotechnology-empowered strategies in treatment of skin cancer

J Chandra, N Hasan, N Nasir, S Wahab… - Environmental …, 2023 - Elsevier
In current scenario skin cancer is a serious condition that has a significant impact on world
health. Skin cancer is divided into two categories: melanoma skin cancer (MSC) and non …

Immunomodulatory and allergenic properties of antimicrobial peptides

SV Guryanova, TV Ovchinnikova - International journal of molecular …, 2022 - mdpi.com
With the growing problem of the emergence of antibiotic-resistant bacteria, the search for
alternative ways to combat bacterial infections is extremely urgent. While analyzing the effect …

[HTML][HTML] From oncolytic peptides to oncolytic polymers: A new paradigm for oncotherapy

H Liu, W Shen, W Liu, Z Yang, D Yin, C Xiao - Bioactive Materials, 2024 - Elsevier
Traditional cancer therapy methods, especially those directed against specific intracellular
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …

Anticancer peptides mechanisms, simple and complex

P Norouzi, M Mirmohammadi, MHH Tehrani - Chemico-Biological …, 2022 - Elsevier
Peptide therapy has started since 1920s with the advent of insulin application, and now it
has emerged as a new approach in treatment of diseases including cancer. Using anti …

Tumour–host interactions through the lens of Drosophila

D Bilder, K Ong, TC Hsi, K Adiga, J Kim - Nature Reviews Cancer, 2021 - nature.com
There is a large gap between the deep understanding of mechanisms driving tumour growth
and the reasons why patients ultimately die of cancer. It is now appreciated that interactions …

Versatile peptide-based nanosystems for photodynamic therapy

Q Li, R Ming, L Huang, R Zhang - Pharmaceutics, 2024 - mdpi.com
Photodynamic therapy (PDT) has become an important therapeutic strategy because it is
highly controllable, effective, and does not cause drug resistance. Moreover, precise …