Pathophysiology of motor dysfunction in Parkinson's disease as the rationale for drug treatment and rehabilitation
F Magrinelli, A Picelli, P Tocco, A Federico… - Parkinson's …, 2016 - Wiley Online Library
Cardinal motor features of Parkinson's disease (PD) include bradykinesia, rest tremor, and
rigidity, which appear in the early stages of the disease and largely depend on …
rigidity, which appear in the early stages of the disease and largely depend on …
Prevalence of freezing of gait in Parkinson's disease: a systematic review and meta-analysis
WS Zhang, C Gao, YY Tan, SD Chen - Journal of neurology, 2021 - Springer
Background Freezing of gait (FOG) is considered one of the most disturbing and least
understood symptoms in Parkinson's disease (PD). The reported prevalence rates of FOG in …
understood symptoms in Parkinson's disease (PD). The reported prevalence rates of FOG in …
[HTML][HTML] Model-based and model-free machine learning techniques for diagnostic prediction and classification of clinical outcomes in Parkinson's disease
In this study, we apply a multidisciplinary approach to investigate falls in PD patients using
clinical, demographic and neuroimaging data from two independent initiatives (University of …
clinical, demographic and neuroimaging data from two independent initiatives (University of …
[HTML][HTML] Diffusion tensor imaging in Parkinson's disease: review and meta-analysis
Background Neuroimaging studies help us better understand the pathophysiology and
symptoms of Parkinson's disease (PD). In several of these studies, diffusion tensor imaging …
symptoms of Parkinson's disease (PD). In several of these studies, diffusion tensor imaging …
The functional network signature of heterogeneity in freezing of gait
Freezing of gait is a complex, heterogeneous, and highly variable phenomenon whose
pathophysiology and neural signature remains enigmatic. Evidence suggests that freezing is …
pathophysiology and neural signature remains enigmatic. Evidence suggests that freezing is …
Brain structural and functional connectivity in P arkinson's disease with freezing of gait
Objective To use a multimodal approach to assess brain structural pathways and resting
state (RS) functional connectivity abnormalities in patients with Parkinson's disease and …
state (RS) functional connectivity abnormalities in patients with Parkinson's disease and …
The next step: a common neural mechanism for freezing of gait
SJG Lewis, JM Shine - The Neuroscientist, 2016 - journals.sagepub.com
Freezing of gait is a disabling symptom of Parkinson's disease that causes a paroxysmal
cessation of normal footsteps while walking. Despite a great deal of empirical research, the …
cessation of normal footsteps while walking. Despite a great deal of empirical research, the …
[HTML][HTML] Repetitive transcranial magnetic stimulation improves Parkinson's freezing of gait via normalizing brain connectivity
Robust, effective treatments for Parkinson's freezing of gait remain elusive. Our previous
study revealed beneficial effects of high-frequency rTMS over the supplementary motor area …
study revealed beneficial effects of high-frequency rTMS over the supplementary motor area …
Cognition and freezing of gait in Parkinson's disease: A systematic review and meta-analysis
Freezing of gait (FOG) is a common and disabling symptom in people with Parkinson's
Disease (PwPD). Although cognition is thought to be worse in PwPD who freeze, a …
Disease (PwPD). Although cognition is thought to be worse in PwPD who freeze, a …
Gait and balance in Parkinson's disease subtypes: objective measures and classification considerations
T Herman, A Weiss, M Brozgol, N Giladi… - Journal of …, 2014 - Springer
Parkinson's disease (PD) is often divided into tremor dominant (TD) and postural instability
gait difficulty (PIGD) subtypes. However, objective measures of gait (eg, stride length …
gait difficulty (PIGD) subtypes. However, objective measures of gait (eg, stride length …