Machine learning in drug discovery: a review

S Dara, S Dhamercherla, SS Jadav, CHM Babu… - Artificial intelligence …, 2022 - Springer
This review provides the feasible literature on drug discovery through ML tools and
techniques that are enforced in every phase of drug development to accelerate the research …

Artificial intelligence-based multi-omics analysis fuels cancer precision medicine

X He, X Liu, F Zuo, H Shi, J Jing - Seminars in Cancer Biology, 2023 - Elsevier
With biotechnological advancements, innovative omics technologies are constantly
emerging that have enabled researchers to access multi-layer information from the genome …

Deep neural network models for computational histopathology: A survey

CL Srinidhi, O Ciga, AL Martel - Medical image analysis, 2021 - Elsevier
Histopathological images contain rich phenotypic information that can be used to monitor
underlying mechanisms contributing to disease progression and patient survival outcomes …

Applications of machine learning in drug discovery and development

J Vamathevan, D Clark, P Czodrowski… - Nature reviews Drug …, 2019 - nature.com
Drug discovery and development pipelines are long, complex and depend on numerous
factors. Machine learning (ML) approaches provide a set of tools that can improve discovery …

[HTML][HTML] A review on deep learning approaches in healthcare systems: Taxonomies, challenges, and open issues

S Shamshirband, M Fathi, A Dehzangi… - Journal of Biomedical …, 2021 - Elsevier
In the last few years, the application of Machine Learning approaches like Deep Neural
Network (DNN) models have become more attractive in the healthcare system given the …

Deep learning models for histopathological classification of gastric and colonic epithelial tumours

O Iizuka, F Kanavati, K Kato, M Rambeau, K Arihiro… - Scientific reports, 2020 - nature.com
Histopathological classification of gastric and colonic epithelial tumours is one of the routine
pathological diagnosis tasks for pathologists. Computational pathology techniques based on …

A comprehensive review of computer-aided whole-slide image analysis: from datasets to feature extraction, segmentation, classification and detection approaches

X Li, C Li, MM Rahaman, H Sun, X Li, J Wu… - Artificial Intelligence …, 2022 - Springer
With the development of Computer-aided Diagnosis (CAD) and image scanning techniques,
Whole-slide Image (WSI) scanners are widely used in the field of pathological diagnosis …

Emerging role of deep learning‐based artificial intelligence in tumor pathology

Y Jiang, M Yang, S Wang, X Li… - Cancer communications, 2020 - Wiley Online Library
The development of digital pathology and progression of state‐of‐the‐art algorithms for
computer vision have led to increasing interest in the use of artificial intelligence (AI) …

Artificial intelligence to identify genetic alterations in conventional histopathology

D Cifci, S Foersch, JN Kather - The Journal of Pathology, 2022 - Wiley Online Library
Precision oncology relies on the identification of targetable molecular alterations in tumor
tissues. In many tumor types, a limited set of molecular tests is currently part of standard …

Adversarial attacks and adversarial robustness in computational pathology

N Ghaffari Laleh, D Truhn, GP Veldhuizen… - Nature …, 2022 - nature.com
Artificial Intelligence (AI) can support diagnostic workflows in oncology by aiding diagnosis
and providing biomarkers directly from routine pathology slides. However, AI applications …