Cardio-onco-metabolism: metabolic remodelling in cardiovascular disease and cancer

A Karlstaedt, J Moslehi, RA de Boer - Nature Reviews Cardiology, 2022 - nature.com
Cardiovascular disease and cancer are the two leading causes of morbidity and mortality in
the world. The emerging field of cardio-oncology has revealed that these seemingly …

Redox imbalances in ageing and metabolic alterations: implications in cancer and cardiac diseases. An overview from the working group of cardiotoxicity and …

V Mercurio, A Cuomo, C Cadeddu Dessalvi, M Deidda… - Antioxidants, 2020 - mdpi.com
Metabolic syndrome (MetS) is a well established risk factor for cardiovascular (CV) diseases.
In addition, several studies indicate that MetS correlates with the increased risk of cancer in …

Cancer incidence and mortality according to pre-existing heart failure in a community-based cohort

E Bertero, F Robusto, E Rulli, A D'Ettorre, L Bisceglia… - Cardio Oncology, 2022 - jacc.org
Background Studies assessing whether heart failure (HF) is associated with cancer and
cancer-related mortality have yielded conflicting results. Objectives This study assessed …

Heart failure is associated with an increased incidence of cancer diagnoses

C Roderburg, SH Loosen, JK Jahn… - ESC Heart …, 2021 - Wiley Online Library
Aims The prognosis and quality of life of heart failure patients is determined to a significant
extent by co‐morbidities. New data suggest that heart failure may be associated with an …

Network meta‐analysis of medical therapy efficacy in more than 90,000 patients with heart failure and reduced ejection fraction

V De Marzo, G Savarese, L Tricarico… - Journal of internal …, 2022 - Wiley Online Library
Background Following the availability of new drugs for chronic heart failure (HF) with
reduced ejection fraction (HFrEF), we sought to provide an updated and comparative …

Temporal trends in the incidence of malignancy in heart failure: a nationwide Danish study

J Bruhn, M Malmborg, CH Garred, P Ravn… - European heart …, 2023 - academic.oup.com
Aims Cancer and heart failure (HF) share risk factors, pathophysiological mechanisms, and
possibly genetics. Improved HF survival may increase the risk of cancer due to a competing …

Cancer is a comorbidity of heart failure

P Ameri, E Bertero, WC Meijers - European heart journal, 2023 - academic.oup.com
In the last 5 years, growing attention has been paid to the occurrence of cancer in
individuals who already have heart failure (HF). 1 The issue of cancer in HF was further …

Characteristics and outcomes of patients with a history of cancer recruited to heart failure trials

SJH Dobbin, L Shen, MC Petrie… - European Journal of …, 2023 - Wiley Online Library
Aims Heart failure (HF) therapy trials usually exclude cancer patients. We examined the
association between cancer history and outcomes in trial participants with HF and reduced …

Heart failure pharmacotherapy and cancer: pathways and pre-clinical/clinical evidence

NV Sayour, ÁM Paál, P Ameri, WC Meijers… - European Heart …, 2024 - academic.oup.com
Heart failure (HF) patients have a significantly higher risk of new-onset cancer and cancer-
associated mortality, compared to subjects free of HF. While both the prevention and …

RAAS: a convergent player in ischemic heart failure and cancer

TC Garcia-Garduño, JR Padilla-Gutierrez… - International journal of …, 2021 - mdpi.com
The current global prevalence of heart failure is estimated at 64.34 million cases, and it is
expected to increase in the coming years, especially in countries with a medium-low …