Microfluidic single‐cell omics analysis

X Xu, J Wang, L Wu, J Guo, Y Song, T Tian, W Wang… - Small, 2020 - Wiley Online Library
The commonly existing cellular heterogeneity plays a critical role in biological processes
such as embryonic development, cell differentiation, and disease progress. Single‐cell …

New horizons in developing cell lysis methods: A review

M Danaeifar - Biotechnology and Bioengineering, 2022 - Wiley Online Library
Cell lysis is an essential step in many studies related to biology and medicine. Based on the
scale and medium that cell lysis is carried out, there are three main types of the cell lysis:(1) …

Review of microfluidic methods for cellular lysis

E Grigorov, B Kirov, MB Marinov, V Galabov - Micromachines, 2021 - mdpi.com
Cell lysis is a process in which the outer cell membrane is broken to release intracellular
constituents in a way that important information about the DNA or RNA of an organism can …

Emerging microfluidic devices for cell lysis: a review

L Nan, Z Jiang, X Wei - Lab on a Chip, 2014 - pubs.rsc.org
Intracellular components containing information about genetic and disease characteristics
are key substances to clinical diagnostics. Cell lysis is therefore a crucial step for efficient …

Electricity-free amplification and detection for molecular point-of-care diagnosis of HIV-1

J Singleton, JL Osborn, L Lillis, K Hawkins, D Guelig… - PloS one, 2014 - journals.plos.org
In resource-limited settings, the lack of decentralized molecular diagnostic testing and
sparse access to centralized medical facilities can present a critical barrier to timely …

Low cost extraction and isothermal amplification of DNA for infectious diarrhea diagnosis

S Huang, J Do, M Mahalanabis, A Fan, L Zhao… - PLoS …, 2013 - journals.plos.org
In order to counter the common perception that molecular diagnostics are too complicated to
work in low resource settings, we have performed a difficult sample preparation and DNA …

Nanowire-integrated microfluidic devices for facile and reagent-free mechanical cell lysis

J Kim, JW Hong, DP Kim, JH Shin, I Park - Lab on a Chip, 2012 - pubs.rsc.org
Cell lysis is an essential task for the detection of intracellular components. In this work, we
introduce novel microfluidic devices integrated with patterned one-dimensional …

Highly efficient on-chip photothermal cell lysis for nucleic acid extraction using localized plasmonic heating of strongly absorbing Au nanoislands

ES Yu, BH Kang, MS Ahn, JH Jung… - … Applied Materials & …, 2023 - ACS Publications
Cell lysis serves as an essential role in the sample preparation for intracellular material
extraction in lab-on-a-chip applications. However, recent microfluidic-based cell lysis chips …

Vertically configured nanostructure-mediated electroporation: a promising route for intracellular regulations and interrogations

AR Shokouhi, S Aslanoglou, D Nisbet… - Materials …, 2020 - pubs.rsc.org
The ability to generate programmable vertically aligned 1D nanoscale substrate topography
has spurred advances in five fields of cellular nanotechnology: nanoelectrode-based …

Development of nanowire-modified electrodes applied in the locally enhanced electric field treatment (LEEFT) for water disinfection

J Zhou, C Yu, T Wang, X Xie - Journal of Materials Chemistry A, 2020 - pubs.rsc.org
Locally enhanced electric field treatment (LEEFT) is introduced as a nanowire-enabled
physical water disinfection method with the advantages of low energy consumption, wide …