Herein, we review mechanisms regulating cerebral blood flow (CBF), with specific focus on
humans. We revisit important concepts from the older literature and describe the interaction …

Cerebrovascular reactivity is the change in cerebral blood flow in response to a vasodilatory
or vasoconstrictive stimulus. Measuring variations of cerebrovascular reactivity between …

Decreased cerebrovascular blood flow and function are associated with lower cognitive
functioning and increased risk of neurodegenerative diseases. Prolonged sitting impairs …

Intact, coordinated, and precisely regulated cerebrovascular responses are required for the
maintenance of cerebral metabolic homeostasis, adequate perfusion, oxygen delivery, and …

Exercise is a uniquely effective and pluripotent medicine against several noncommunicable
diseases of westernised lifestyles, including protection against neurodegenerative …

Optimizing cerebral perfusion is key to rescuing salvageable ischemic brain tissue. Despite
being an important determinant of cerebral perfusion, there are no effective guidelines for …

Cerebral hemodynamics, eg, cerebral blood flow, can be measured and quantified using
many different methods, with transcranial Doppler ultrasound (TCD) being one of the most …

It is generally considered that regular exercise maintains brain health and reduces the risk of
cerebrovascular diseases such as stroke and dementia. Since the benefits of different …

New Findings What is the topic of this review? Cerebrovascular reactivity to CO2, which is a
principal factor in determining ventilatory responses to CO2 through the role reactivity plays …

New Findings What is the central question of this study? Cerebrovascular reactivity (CVR) is
a common functional test to assess brain health, and impaired CVR has been associated …