Overcoming barriers to patient adherence: the case for developing innovative drug delivery systems

TH Baryakova, BH Pogostin, R Langer… - Nature Reviews Drug …, 2023 - nature.com
Poor medication adherence is a pervasive issue with considerable health and
socioeconomic consequences. Although the underlying reasons are generally understood …

Barriers to the wider use of pre-exposure prophylaxis in the United States: a narrative review

KH Mayer, A Agwu, D Malebranche - Advances in therapy, 2020 - Springer
Antiretroviral pre-exposure prophylaxis (PrEP) to prevent HIV transmission was first
approved by the US Food and Drug Administration in 2012. Despite correlations of …

Cabotegravir for the prevention of HIV-1 in women: results from HPTN 084, a phase 3, randomised clinical trial

S Delany-Moretlwe, JP Hughes, P Bock, SG Ouma… - The Lancet, 2022 - thelancet.com
Background Oral pre-exposure prophylaxis has been introduced in more than 70 countries,
including many in sub-Saharan Africa, but women experience considerable barriers to daily …

[HTML][HTML] Cabotegravir for HIV prevention in cisgender men and transgender women

RJ Landovitz, D Donnell, ME Clement… - … England Journal of …, 2021 - Mass Medical Soc
Background Safe and effective long-acting injectable agents for preexposure prophylaxis
(PrEP) for human immunodeficiency virus (HIV) infection are needed to increase the options …

Emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis (DISCOVER): primary results from a …

KH Mayer, JM Molina, MA Thompson, PL Anderson… - The Lancet, 2020 - thelancet.com
Background Tenofovir alafenamide shows high antiviral efficacy and improved renal and
bone safety compared with tenofovir disoproxil fumarate when used for HIV treatment. Here …

Clinical targeting of HIV capsid protein with a long-acting small molecule

JO Link, MS Rhee, WC Tse, J Zheng, JR Somoza… - Nature, 2020 - nature.com
Oral antiretroviral agents provide life-saving treatments for millions of people living with HIV,
and can prevent new infections via pre-exposure prophylaxis,,,–. However, some people …

Association of HIV preexposure prophylaxis with incidence of sexually transmitted infections among individuals at high risk of HIV infection

MW Traeger, VJ Cornelisse, J Asselin, B Price, NJ Roth… - Jama, 2019 - jamanetwork.com
Importance Emerging evidence suggests that risk of bacterial sexually transmitted infections
(STIs) increases among gay and bisexual men following initiation of HIV preexposure …

中国艾滋病防治面临新形势与新挑战

吴尊友 - 中国公共卫生, 2011 - cqvip.com
今年是世界艾滋病流行以来的第30 个年头, 全球艾滋病流行与防治形势都发生了巨大的变化.
自上世纪九十年代中期高效联合抗逆转录病毒治疗(highly active antiretroviral therapy …

Sexually transmitted infections: challenges ahead

M Unemo, CS Bradshaw, JS Hocking… - The Lancet infectious …, 2017 - thelancet.com
WHO estimated that nearly 1 million people become infected every day with any of four
curable sexually transmitted infections (STIs): chlamydia, gonorrhoea, syphilis, and …

[HTML][HTML] HIV preexposure prophylaxis, by race and ethnicity—United States, 2014–2016

AH Ya-lin - MMWR. Morbidity and mortality weekly report, 2018 - cdc.gov
HIV Preexposure Prophylaxis, by Race and Ethnicity — United States, 2014–2016 | MMWR
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