Human umbilical cord mesenchymal stem cells: an overview of their potential in cell-based therapy

T Li, M Xia, Y Gao, Y Chen, Y Xu - Expert opinion on biological …, 2015 - Taylor & Francis
Introduction: Human umbilical cord mesenchymal stem cells (HUC-MSCs) are one of the
typical adult stem cells; they have superiorities including low immunogenicity, non-invasive …

Standardization of Good Manufacturing Practice–compliant production of bone marrow–derived human mesenchymal stromal cells for immunotherapeutic …

P Wuchter, K Bieback, H Schrezenmeier… - Cytotherapy, 2015 - Elsevier
Background aims Human mesenchymal stem or stromal cells (MSCs) represent a potential
resource not only for regenerative medicine but also for immunomodulatory cell therapies …

[HTML][HTML] Principal criteria for evaluating the quality, safety and efficacy of hMSC-based products in clinical practice: current approaches and challenges

JA Guadix, J López-Beas, B Clares, JL Soriano-Ruiz… - Pharmaceutics, 2019 - mdpi.com
Human Mesenchymal Stem Cells (hMSCs) play an important role as new therapeutic
alternatives in advanced therapies and regenerative medicine thanks to their regenerative …

Optimizing isolation culture and freezing methods to preserve W harton's jelly's mesenchymal stem cell (MSC) properties: an MSC banking protocol validation for the H …

TK Chatzistamatiou, AC Papassavas… - …, 2014 - Wiley Online Library
Background Mesenchymal stem or stromal cells (MSC s) are a heterogeneous population
that can be isolated from many tissues including umbilical cord W harton's jelly (UC‐WJ) …

[HTML][HTML] Therapeutic potential of Wharton's jelly mesenchymal stem cells for diabetes: achievements and challenges

MM Kamal, DH Kassem - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Diabetes mellitus (DM) is an alarming metabolic disease in which insulin secreting β-cells
are damaged to various extent. Unfortunately, although currently available treatments help …

Biomaterial-assisted scalable cell production for cell therapy

R Chen, L Li, L Feng, Y Luo, M Xu, KW Leong, R Yao - Biomaterials, 2020 - Elsevier
Cell therapy, the treatment of diseases using living cells, offers a promising clinical approach
to treating refractory diseases. The global market for cell therapy is growing rapidly, and …

A simple and serum-free protocol for cryopreservation of human umbilical cord as source of Wharton's jelly mesenchymal stem cells

S Roy, S Arora, P Kumari, M Ta - Cryobiology, 2014 - Elsevier
Mesenchymal stromal cells (MSCs) show promise in cell-based transplantations and
regenerative medicine applications. MSCs from Wharton's jelly (WJ) of umbilical cord can be …

Biobanking of human mesenchymal stem cells: future strategy to facilitate clinical applications

KW Yong, JR Choi, WKZ Wan Safwani - Biobanking and cryopreservation …, 2016 - Springer
Human mesenchymal stem cells (hMSCs), a type of adult stem cells that hold great potential
in clinical applications (eg, regenerative medicine and cell-based therapy) due to their ability …

Advances in cell encapsulation technology and its application in drug delivery

H Gurruchaga, L Saenz del Burgo, J Ciriza… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Cell encapsulation technology has improved enormously since it was proposed
50 years ago. The advantages offered over other alternative systems, such as the prevention …

[HTML][HTML] Cryopreservation of human Wharton's jelly-derived mesenchymal stem cells following controlled rate freezing protocol using different cryoprotectants; a …

SB Shivakumar, D Bharti, SJ Jang… - Int. J. Stem …, 2015 - synapse.koreamed.org
Objectives To compare the effect of three different cryoprotectants on basic stem cell
characteristics for the possibility of using well defined, dimethyl sulfoxide (DMSO) and serum …