ESC Guidelines e341 (1) the specific situation of the patient. In this respect, it is specified
that, unless otherwise provided for by national regulations, offlabel use of medication should …

Light chain deposition disease (LCDD) is a rare hematologic disorder characterized by the
deposition of non-amyloid monoclonal light chains in several organs. Together with renal …

Monoclonal immunoglobulin deposition disease (MIDD) is a rare complication of B-cell
clonal disorders, defined by Congo red negative–deposits of monoclonal light chain …

The purpose of this review is to give an overview on the conceptual framework and major
developments of the upcoming 5th edition of the World Health Organization (WHO) …

Free light chains (FLCs) induce inflammatory pathways in proximal tubule cells (PTCs). The
role of TLRs in these responses is unknown. Here we present findings on the role of TLRs in …

Long‐term outcomes in light chain deposition disease‐ analysis of a UK cohort Page 1 Long-term
outcomes in light chain deposition disease- analysis of a UK cohort Sriram Ravichandran …

Unlike AL amyloid and cast nephropathy, the long‐term outcomes of monoclonal
gammopathy of renal significance (MGRS) patients with other renal histopathologies remain …

Monoclonal immunoglobulin deposition disease (MIDD), often associated with plasma cell
dyscrasias, predominantly affects the kidneys. In this disease, hematologic response (HR) to …

B cells play a central role in the pathogenesis of many autoimmune diseases, acting as
antigen-presenting cells, producing inflammatory cytokines, and acting as a source of …

Introduction Monoclonal Ig deposition disease (MIDD) frequently leads to kidney failure, and
a large proportion of these patients would greatly benefit from kidney transplantation …