Over the recent years the wider availability and application of state-of-the-art immunological
technologies greatly advanced the insight into the mechanisms that play an important role in …

The 'MHC-I (major histocompatibility complex class I)-opathy'concept describes a family of
inflammatory conditions with overlapping clinical manifestations and a strong genetic link to …

The gut microbiome plays a pivotal role in maintaining the health of the hosts; however,
there is accumulating evidence that certain bacteria in the host, termed pathobionts, play …

ABSTRACT Salmonella enterica serovar Typhimurium (STm) causes gastroenteritis and can
progress to reactive arthritis (ReA). STm forms biofilms in the gut that secrete the amyloid …

Osteoblasts and osteoclasts collaborate in bone metabolism, facilitating bone development,
maintaining normal bone density and strength, and aiding in the repair of pathological …

Research on the influence of gut microbiota on systemic inflammatory arthritis has exploded
in the past decade. Gut microbiota changes may be a crucial regulatory component in …

Ankylosing spondylitis (AS) is an autoinflammatory disease that affects the sacroiliac joints,
causing stiffness and pain in the back. MICA is a ligand of the NKG2D receptor, and an …

Autoimmune (or rheumatic) diseases are increasing in prevalence but selecting the best
therapy for each patient proceeds in trial‐and‐error fashion. This strategy can lead to …

The pathogenesis and pathophysiology of Ankylosing Spondylitis (AS) is complex and
remains only partially understood. Contributory genes including a variety of HLA-B27 subset …

Spondyloarthritis (SpA) describes a group of diseases characterized by chronic
inflammation in the spine and peripheral joints. While pathogenesis is still unclear …