An overview of pyridazin-3(2H)-one: a core for developing bioactive agents targeting cardiovascular diseases and cancer
ZS Abd-Rabo, AM Serry, RF George - Future Medicinal Chemistry, 2024 - Taylor & Francis
Cardiovascular diseases (CVDs) and cancer are the top two leading causes of death
globally. Vasodilators are commonly used to treat various CVDs. In cancer treatment …
globally. Vasodilators are commonly used to treat various CVDs. In cancer treatment …
Ocular delivery of felodipine for the management of intraocular pressure and inflammation: Effect of film plasticizer and in vitro in vivo evaluation
R Swain, A Moharana, S Habibullah, S Nandi… - International Journal of …, 2023 - Elsevier
Glaucoma may cause irreversible eyesight loss and damage to the optic nerve. Trabecular
meshwork obstruction may raise intraocular pressure (IOP) in open-angle and/or closed …
meshwork obstruction may raise intraocular pressure (IOP) in open-angle and/or closed …
Enhancing Oral Drug Absorption: Overcoming Physiological and Pharmaceutical Barriers for Improved Bioavailability
The oral route stands out as the most commonly used method for drug administration, prized
for its non-invasive nature, patient compliance, and easy administration. Several elements …
for its non-invasive nature, patient compliance, and easy administration. Several elements …
Lipid-Gelucire based rectal delivery of ramipril prodrug exhibits significant lowering of intra-ocular pressure in normotensive rabbit: Sustained structural relaxation …
S Nandi, R Swain, S Habibullah… - Pharmaceutical …, 2024 - Taylor & Francis
Carboxylesterase enzymes convert a prodrug ramipril into the biologically active metabolite
ramiprilat. It is prescribed for controlling ocular hypertension after oral administration. High …
ramiprilat. It is prescribed for controlling ocular hypertension after oral administration. High …