Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts

MP Stewart, R Langer, KF Jensen - Chemical reviews, 2018 - ACS Publications
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery

J Deprez, G Lajoinie, Y Engelen, SC De Smedt… - Advanced drug delivery …, 2021 - Elsevier
Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …

[HTML][HTML] Nanoparticle-assisted ultrasound: A special focus on sonodynamic therapy against cancer

G Canavese, A Ancona, L Racca, M Canta… - Chemical Engineering …, 2018 - Elsevier
At present, ultrasound radiation is broadly employed in medicine for both diagnostic and
therapeutic purposes at various frequencies and intensities. In this review article, we focus …

Understanding ultrasound induced sonoporation: definitions and underlying mechanisms

I Lentacker, I De Cock, R Deckers, SC De Smedt… - Advanced drug delivery …, 2014 - Elsevier
In the past two decades, research has underlined the potential of ultrasound and
microbubbles to enhance drug delivery. However, there is less consensus on the …

[HTML][HTML] A human clinical trial using ultrasound and microbubbles to enhance gemcitabine treatment of inoperable pancreatic cancer

G Dimcevski, S Kotopoulis, T Bjånes, D Hoem… - Journal of Controlled …, 2016 - Elsevier
Background The primary aim of our study was to evaluate the safety and potential toxicity of
gemcitabine combined with microbubbles under sonication in inoperable pancreatic cancer …

[HTML][HTML] Ultrasound technology for food fermentation applications

KS Ojha, TJ Mason, CP O'Donnell, JP Kerry… - Ultrasonics …, 2017 - Elsevier
Fermentation processes involve the participation of enzymes and organic catalysts,
generated by range of microorganisms to produce chemical transformations. Ultrasound can …

Advances in the mechanism of different antibacterial strategies based on ultrasound technique for controlling bacterial contamination in food industry

J Dai, M Bai, C Li, H Cui, L Lin - Trends in Food Science & Technology, 2020 - Elsevier
Background Pathogenic bacteria contamination has been a global health challenge in the
food industry. In this context, ultrasound technique is attracting much more attention as an …

[HTML][HTML] Evolution of contrast agents for ultrasound imaging and ultrasound-mediated drug delivery

V Paefgen, D Doleschel, F Kiessling - Frontiers in pharmacology, 2015 - frontiersin.org
Ultrasound (US) is one of the most frequently used diagnostic methods. It is a non-invasive,
comparably inexpensive imaging method with a broad spectrum of applications, which can …

Biodegradable polymeric nanoparticles for therapeutic cancer treatments

J Karlsson, HJ Vaughan, JJ Green - Annual review of chemical …, 2018 - annualreviews.org
Polymeric nanoparticles have tremendous potential to improve the efficacy of therapeutic
cancer treatments by facilitating targeted delivery to a desired site. The physical and …

[HTML][HTML] Ultrasound-guided drug delivery in cancer

SM Chowdhury, T Lee, JK Willmann - Ultrasonography, 2017 - ncbi.nlm.nih.gov
Recent advancements in ultrasound and microbubble (USMB) mediated drug delivery
technology has shown that this approach can improve spatially confined delivery of drugs …