A guide of column selection for two-dimensional liquid chromatography method development of natural alkaloids
Y Xu, Y Liu, H Zhou, R Wang, D Yu, Z Guo, X Liang - Talanta, 2023 - Elsevier
Natural products, especially alkaloids, are one of the most valuable, potential drug leads in
drug discovery. As an efficient tool for complex samples, two-dimensional liquid …
drug discovery. As an efficient tool for complex samples, two-dimensional liquid …
Sequential purification of cannabidiol by two-dimensional liquid chromatography combined with modeling and simulation of elution profiles
MH Ardakani, H Rezadoost, HR Norouzi - Journal of Chromatography A, 2024 - Elsevier
Cannabidiol (CBD) has garnered significant attention for its neuroprotective properties, and
research on its therapeutic effects has increased dramatically in recent years. However, the …
research on its therapeutic effects has increased dramatically in recent years. However, the …
Less configuration and more dimensionality: preparative heart-cut multidimensional liquid chromatography based on trapping arrays
Y Zhai, G Li, K Peng, Z Ge, W Zhang, D Li - Analytical Chemistry, 2022 - ACS Publications
The resolving power of multiple dimensional liquid chromatography (mD-LC) is
multiplicative as it adds dimensions. However, the issue in creating a preparative mD-LC …
multiplicative as it adds dimensions. However, the issue in creating a preparative mD-LC …
Analysis of alkaloids in Gelsemium elegans Benth using an online heart-cutting+ comprehensive RPLC× RPLC system tandem mass spectrometry
D Liu, Y Liu, A Shen, X Li, L Yu, C Wang, X Liang - Talanta, 2022 - Elsevier
Abstract Characterization of alkaloids and new compound discovery become increasing
challenging for Gelsemium elegans Benth.(G. elegans), due to the lack of an effective …
challenging for Gelsemium elegans Benth.(G. elegans), due to the lack of an effective …
Optimizing the preparative capacity of two-dimensional liquid chromatography based on analytes retention behaviors
G Sun, Z Zhang, L Yang, J Jiang, W Yao, L Pan… - … of Chromatography A, 2023 - Elsevier
In this work, a solute retention optimization method (SRO) was proposed to exploit the
purification potential of two-dimensional liquid chromatography (2D-LC). According to our …
purification potential of two-dimensional liquid chromatography (2D-LC). According to our …
An efficient method for the preparative isolation and purification of alkaloids from Gelsemium by using high speed counter-current chromatography and preparative …
LL Liang, XJ Zhao, Y Lu, SH Zhu, Q Tang… - Preparative …, 2024 - Taylor & Francis
We established an efficient method using high-speed countercurrent chromatography
(HSCCC) combined with preparative high-performance liquid chromatography (prep-HPLC) …
(HSCCC) combined with preparative high-performance liquid chromatography (prep-HPLC) …
Integrated strategy for the screening of cyclooxygenase‐2 inhibitors from triterpenoid saponins in Clematis tangutica
Y Wei, T Chen, S Wang, C Shen, Z Song… - Phytochemical …, 2023 - Wiley Online Library
Introduction Screening of novel cyclooxygenase‐2 (COX‐2) inhibitors from complex natural
products is not an easy task. Objectives To establish an efficient and feasible strategy for …
products is not an easy task. Objectives To establish an efficient and feasible strategy for …
Molecular identification and functional characterization of a transcription factor GeRAV1 from Gelsemium elegans
T Cui, S Zang, X Sun, J Zhang, Y Su, D Wang, G Wu… - BMC genomics, 2024 - Springer
Background Gelsemium elegans is a traditional Chinese medicinal plant and temperature is
one of the key factors affecting its growth. RAV (related to ABI3/VP1) transcription factor …
one of the key factors affecting its growth. RAV (related to ABI3/VP1) transcription factor …
Targeted isolation of cyclooxygenase-2 inhibitors from Saussurea obvallata using affinity ultrafiltration combined with preparative liquid chromatography
W Wang, L Mei, H Yue, Y Tao, Z Liu - Journal of Chromatography B, 2023 - Elsevier
Saussurea obvallata (S. obvallata) is widely used in Qinghai-Tibet Plateau with high
medicinal and edible values of reducing inflammation. But, the individual components and …
medicinal and edible values of reducing inflammation. But, the individual components and …
Bioactivity-guided isolation of cyclooxygenase-2 inhibitors from Saussurea obvallata (DC.) Edgew. Using affinity solid phase extraction assay
W Wang, L Jiang, Y Zhu, L Mei, Y Tao, Z Liu - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Saussurea obvallata (DC.) Edgew. is a traditional Tibetan
medicine used for the treatment of inflammation-related diseases, but the scientific validation …
medicine used for the treatment of inflammation-related diseases, but the scientific validation …