Leptin is a hormone primarily produced by the adipose tissue in proportion to the size of fat
stores, with a primary function in the control of lipid reserves. Besides adipose tissue, leptin …

Recent evidence revealed extra skeleton activity of vitamin D, including prevention from
cardiometabolic diseases and cancer development as well as anti-inflammatory properties …

The discovery of leptin was intrinsically associated with its ability to regulate body weight.
However, the effects of leptin are more far-reaching and include profound glucose-lowering …

Numerous studies have shown that vitamin D deficiency is very common in modern societies
and is perceived as an important risk factor in the development of insulin resistance and …

Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

Adipose tissue plays an important role in systemic metabolism via the secretion of
adipocytokines and storing and releasing energy. In obesity, adipose tissue becomes …

Vitamin D deficiency has been linked to the onset of diabetes. This review summarizes the
role of Vitamin D in maintaining the normal release of insulin by the pancreatic beta cells (β …

Adipose tissue has long been identified as the major site of vitamin D storage. Recent
studies have demonstrated that VDR and vitamin D metabolizing enzymes are expressed in …

Obesity is a chronic disease that represents one of the most serious global health burdens
associated to an excess of body fat resulting from an imbalance between energy intake and …

Leptin is a hormone discovered almost 30 years ago with important implications in
metabolism. It is primarily produced by white adipose tissue (WAT) in proportion to the …