Engineered biomimetic membranes for organ-on-a-chip

M Rahimnejad, F Rasouli, S Jahangiri… - ACS Biomaterials …, 2022 - ACS Publications
Organ-on-a-chip (OOC) systems are engineered nanobiosystems to mimic the
physiochemical environment of a specific organ in the body. Among various components of …

Skin-on-a-chip technologies towards clinical translation and commercialization

N Ismayilzada, C Tarar, SR Dabbagh, BK Tokyay… - …, 2024 - iopscience.iop.org
Skin is the largest organ of the human body which plays a critical role in thermoregulation,
metabolism (eg synthesis of vitamin D), and protection of other organs from environmental …

Prediction of drug permeation through microneedled skin by machine learning

Y Yuan, Y Han, CW Yap, JS Kochhar… - Bioengineering & …, 2023 - Wiley Online Library
Stratum corneum is the outermost layer of the skin preventing external substances from
entering human body. Microneedles (MNs) are sharp protrusions of a few hundred microns …

[HTML][HTML] Enhancement of skin delivery of drugs using proposome depends on drug lipophilicity

H Kathuria, HK Handral, S Cha, DTP Nguyen, J Cai… - Pharmaceutics, 2021 - mdpi.com
The study aims to investigate the propylene glycol-based liposomes named 'proposomes' in
enhancing skin permeation of drugs with different physicochemical properties. Ibuprofen …

Design and development of a novel fused filament fabrication (FFF) 3D printed diffusion cell with UV imaging capabilities to characterise permeation in pharmaceutical …

Z Fazili, A Ward, K Walton, L Blunt… - European Journal of …, 2020 - Elsevier
The present work aimed at designing and developing a novel 3D printed diffusion cell
capable of UV imaging using the fused filament fabrication (FFF) method. UV imaging has …