Lactation is critical to infant short-term and long-term health and protects mothers from
breast cancer, ovarian cancer and type 2 diabetes mellitus. The mammary gland is a …

The mammary gland (MG) is a unique organ responsible for milk synthesis, secretion, and
involution to prepare the gland for subsequent lactation. The mammary epithelial cells …

High doses of estrogenic pharmaceuticals were once prescribed to women to halt lactation.
Yet, the effects of low-level xenoestrogens on lactation remain poorly studied. We …

Many clinical and preclinical studies report higher prevalence and severity of chronic pain in
females. We used hyperalgesic priming with interleukin 6 (IL-6) priming and PGE 2 as a …

Abstract Background Copy number variations (CNVs) are important and widely distributed in
the genome. CNV detection opens a new avenue for exploring genes associated with …

Many clinical and preclinical studies report an increased prevalence and severity of chronic
pain among females. Here, we identify a sex-hormone-controlled target and mechanism that …

Thyroid pathologies have deleterious effects on lactation. Especially hypothyroidism
(HypoT) induces premature mammary involution at the end of lactation and decreases milk …

Hypothyroidism is a protective factor against breast cancer but long-term exposure or
overdoses of thyroid replacement therapy with thyroxine (T 4) may increase breast cancer …

Prolactin is an important endocrine activator of lactogenesis. This study investigated the
function and mechanism of miR‐135b in the enhancement of lactation by prolactin in goat …

The absence of the thyroid hormone (TH) could impair testicular function, but its mechanism
is still rudimentary. This study aims to explore the roles of estrogen receptor (ER α, β) and G …