[HTML][HTML] Terpenes and terpenoids as main bioactive compounds of essential oils, their roles in human health and potential application as natural food preservatives

A Masyita, RM Sari, AD Astuti, B Yasir, NR Rumata… - Food chemistry: X, 2022 - Elsevier
Essential oils (EOs) are volatile and concentrated liquids extracted from different parts of
plants. Bioactive compounds found in EOs, especially terpenes and terpenoids possess a …

Immunity and inflammation in pulmonary arterial hypertension: From pathophysiology mechanisms to treatment perspective

R Wang, T Yuan, J Wang, Y Chen, J Zhao, M Li… - Pharmacological …, 2022 - Elsevier
Pulmonary arterial hypertension (PAH) is a severe cardiopulmonary dysfunctional disease,
characterized by progressive vascular remodeling. Inflammation is an increasingly …

Perillyl alcohol attenuates rheumatoid arthritis via regulating TLR4/NF-κB and Keap1/Nrf2 signaling pathways: A comprehensive study onin-vitro and in-vivo …

ER Puppala, S Jain, P Saha, M Rachamalla… - Phytomedicine, 2022 - Elsevier
Background Rheumatoid arthritis is a chronic and idiopathic autoimmune disorder. Perillyl
alcohol (POH) is a monoterpene which can be extracted from widely available essential oils …

Perillyl alcohol (PA) mitigates inflammatory, oxidative, and histopathological consequences of allergic asthma in rats

MA Bejeshk, A Beik, AH Aminizadeh, F Salimi… - Naunyn-Schmiedeberg's …, 2023 - Springer
Allergic asthma is an inflammatory and chronic condition, which is the most common asthma
phenotype. It is usually defined by sensitivity to environmental allergens and leads to the …

Perillyl alcohol inhibits keratinocyte proliferation and attenuates imiquimod-induced psoriasis like skin-inflammation by modulating NF-κB and STAT3 signaling …

SS Yalamarthi, ER Puppala, M Abubakar… - International …, 2022 - Elsevier
Psoriasis is a chronic inflammatory and proliferative skin disease characterized by
pathological skin lesions which significantly impact the quality of life. Recent studies have …

Preparation and evaluation of preventive effects of inhalational and intraperitoneal injection of Myrtenol loaded Nano-Niosomes on lung ischemia-reperfusion injury in …

MA Bejeshk, H Najafipour, M Khaksari… - Journal of …, 2024 - Elsevier
Introduction Ischemia-reperfusion injury (IRI) is directly related to forming reactive oxygen
species, endothelial cell injury, increased vascular permeability, and the activation of …

Forsythoside B Mitigates Monocrotaline-Induced Pulmonary Arterial Hypertension via Blocking the NF-κB Signaling Pathway to Attenuate Vascular Remodeling

J Liu, G Fang, C Lan, C Qiu, L Yao… - Drug Design …, 2024 - Taylor & Francis
Purpose Pulmonary arterial hypertension (PAH) is a devastating disease with little effective
treatment. The proliferation of pulmonary artery smooth muscle cells (PASMCs) induced by …

[HTML][HTML] Perillyl alcohol and quercetin modulate the expression of non-coding RNAs MIAT, H19, miR-29a, and miR-33a in pulmonary artery hypertension in rats

S Rajabi, H Najafipour, M Sheikholeslami… - Non-coding RNA …, 2022 - Elsevier
Abstract Background Non-coding RNAs, including long non-coding RNAs (lncRNAs) and
microRNAs (miRNAs), play critical roles in the pathogenesis and progression of pulmonary …

Nobiletin attenuates monocrotaline-induced pulmonary arterial hypertension through PI3K/Akt/STAT3 pathway

Q Yin, S Wang, J Yang, C Fan, Y Yu, J Li… - Journal of Pharmacy …, 2023 - academic.oup.com
Objectives Nobiletin is a flavonoid found in the peel of Citrus sinensis (oranges). The
purpose of this study is to investigate whether Nobiletin can alleviate the monocrotaline …

Beneficial effects of berberine against pulmonary complications of experimental pulmonary arterial hypertension in rats and some relevant mechanisms

A Beik, H Najafipour, S Joukar, S Rajabi… - Pulmonary …, 2023 - Wiley Online Library
Pulmonary arterial hypertension (PAH) is a severe disease that leads to pulmonary vascular
remodeling characterized by a rise in pulmonary vascular resistance and pressure. We …