Endothelial dysfunction in chronic kidney disease, from biology to clinical outcomes: a 2020 update

S Roumeliotis, F Mallamaci, C Zoccali - Journal of Clinical Medicine, 2020 - mdpi.com
The vascular endothelium is a dynamic, functionally complex organ, modulating multiple
biological processes, including vascular tone and permeability, inflammatory responses …

Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches

P Düsing, A Zietzer, PR Goody, MR Hosen… - Journal of molecular …, 2021 - Springer
Cardiovascular disease (CVD) is a major cause of death in patients with chronic kidney
disease (CKD). Both conditions are rising in incidence as well as prevalence, creating poor …

Diagnosis, evaluation, prevention, and treatment of chronic kidney disease–mineral and bone disorder: Synopsis of the kidney disease: improving global outcomes …

M Ketteler, GA Block, P Evenepoel… - Annals of internal …, 2018 - acpjournals.org
Description: The Kidney Disease: Improving Global Outcomes (KDIGO) 2017 Clinical
Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of …

Targeting vascular calcification in chronic kidney disease

AJ Nelson, P Raggi, M Wolf, AM Gold… - Basic to Translational …, 2020 - jacc.org
Cardiovascular (CV) disease remains an important cause of morbidity and mortality for
patients with chronic kidney disease (CKD). Although clustering of traditional risk factors with …

Vascular calcification in CKD-MBD: Roles for phosphate, FGF23, and Klotho

S Yamada, CM Giachelli - Bone, 2017 - Elsevier
Vascular calcification (VC) is highly prevalent in aging, diabetes mellitus, and chronic kidney
disease (CKD). VC is a strong predictor of cardiovascular morbidity and mortality in the CKD …

KDOQI US commentary on the 2017 KDIGO clinical practice guideline update for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease …

T Isakova, TL Nickolas, M Denburg… - American Journal of …, 2017 - Elsevier
Chronic kidney disease–mineral and bone disorder (CKD-MBD) encompasses laboratory
and bone abnormalities and vascular calcification and has deleterious effects on clinical …

Effect of calcium-based versus non-calcium-based phosphate binders on mortality in patients with chronic kidney disease: an updated systematic review and meta …

SA Jamal, B Vandermeer, P Raggi, DC Mendelssohn… - The Lancet, 2013 - thelancet.com
Background Phosphate binders (calcium-based and calcium-free) are recommended to
lower serum phosphate and prevent hyperphosphataemia in patients with chronic kidney …

CKD, arterial calcification, atherosclerosis and bone health: Inter-relationships and controversies

AB Reiss, N Miyawaki, J Moon, LJ Kasselman… - Atherosclerosis, 2018 - Elsevier
Mineral bone disease (MBD) is a common complication of chronic kidney disease (CKD)
characterized by disruption of normal mineral homeostasis within the body. One or more of …

Metabolic acidosis of CKD: an update

JA Kraut, NE Madias - American Journal of Kidney Diseases, 2016 - Elsevier
The kidney has the principal role in the maintenance of acid-base balance. Therefore, a
decrease in renal ammonium excretion and a positive acid balance often leading to a …

Mineral bone disorders in kidney disease patients: The ever-current topic

L Hu, A Napoletano, M Provenzano, C Garofalo… - International Journal of …, 2022 - mdpi.com
Chronic kidney disease (CKD) is a complex and multifactorial disease, and one of the most
prevalent worldwide. Chronic kidney disease–mineral bone disorders (CKD–MBD) with …