Development of innovative biomaterials and devices for the treatment of cardiovascular diseases

Y Wang, G Li, L Yang, R Luo, G Guo - Advanced Materials, 2022 - Wiley Online Library
Cardiovascular diseases have become the leading cause of death worldwide. The
increasing burden of cardiovascular diseases has become a major public health problem …

Next-generation tissue-engineered heart valves with repair, remodelling and regeneration capacity

ES Fioretta, SE Motta, V Lintas, S Loerakker… - Nature Reviews …, 2021 - nature.com
Valvular heart disease is a major cause of morbidity and mortality worldwide. Surgical valve
repair or replacement has been the standard of care for patients with valvular heart disease …

Self-healing polyurethane-elastomer with mechanical tunability for multiple biomedical applications in vivo

C Jiang, L Zhang, Q Yang, S Huang, H Shi… - Nature …, 2021 - nature.com
The unique properties of self-healing materials hold great potential in the field of biomedical
engineering. Although previous studies have focused on the design and synthesis of self …

[HTML][HTML] Applications of synthetic polymers in clinical medicine

MF Maitz - Biosurface and Biotribology, 2015 - Elsevier
Multiple biological, synthetic and hybrid polymers are used for multiple medical applications.
A wide range of different polymers is available, and they have further the advantage to be …

Polyetheretherketone (PEEK) for medical applications

IV Panayotov, V Orti, F Cuisinier, J Yachouh - Journal of Materials Science …, 2016 - Springer
Polyetheretherketone (PEEK) is a polyaromatic semi-crystalline thermoplastic polymer with
mechanical properties favorable for bio-medical applications. Polyetheretherketone forms …

Polyphenols as a versatile component in tissue engineering

X Gao, Z Xu, G Liu, J Wu - Acta biomaterialia, 2021 - Elsevier
The fabrication of functional tissue or organs substitutes has always been the pursuit of
goals in the field of tissue engineering. But even biocompatible tissue-engineered scaffolds …

Flaw-insensitive fatigue resistance of chemically fixed collagenous soft tissues

L Zeng, F Liu, Q Yu, C Jin, J Yang, Z Suo, J Tang - Science Advances, 2023 - science.org
Bovine pericardium (BP) has been used as leaflets of prosthetic heart valves. The leaflets
are sutured on metallic stents and can survive 400 million flaps (~ 10-year life span) …

Sterilization of implantable polymer-based medical devices: A review

NP Tipnis, DJ Burgess - International journal of pharmaceutics, 2018 - Elsevier
This review article is focused on the sterilization techniques used for polymer-based
implantable medical devices as well as the regulatory aspects governing sterile medical …

Polymeric prosthetic heart valves: A review of current technologies and future directions

SK Singh, M Kachel, E Castillero, Y Xue… - Frontiers in …, 2023 - frontiersin.org
Valvular heart disease is an important source of cardiovascular morbidity and mortality.
Current prosthetic valve replacement options, such as bioprosthetic and mechanical heart …

[HTML][HTML] The effect of molecular weight and fiber diameter on the mechanical properties of single, electrospun PCL nanofibers

N Alharbi, A Daraei, H Lee, M Guthold - Materials Today Communications, 2023 - Elsevier
Biomaterials based on electrospun nanofibers are increasingly used in biomedical
applications. Polycaprolactone (PCL) is a biocompatible, biodegradable, FDA-approved …