C− H functionalisation for hydrogen isotope exchange
J Atzrodt, V Derdau, WJ Kerr… - Angewandte Chemie …, 2018 - Wiley Online Library
The various applications of hydrogen isotopes (deuterium, D, and tritium, T) in the physical
and life sciences demand a range of methods for their installation in an array of molecular …
and life sciences demand a range of methods for their installation in an array of molecular …
Recent advances in visible-light photocatalytic deuteration reactions
R Zhou, L Ma, X Yang, J Cao - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
Deuterated organic compounds have widespread applications in many fields such as
medicinal chemistry, mechanistic studies, and quantitative analyses. Traditionally, the …
medicinal chemistry, mechanistic studies, and quantitative analyses. Traditionally, the …
Photoredox-catalyzed enantioselective α-deuteration of azaarenes with D2O
T Shao, Y Li, N Ma, C Li, G Chai, X Zhao, B Qiao… - Iscience, 2019 - cell.com
The site-specific incorporation of deuterium (D) into small molecules is frequently used to
access isotopically labeled compounds with broad utility in many research areas, such as …
access isotopically labeled compounds with broad utility in many research areas, such as …
Methoden der C‐H‐Funktionalisierung für den Wasserstoffisotopenaustausch
J Atzrodt, V Derdau, WJ Kerr, M Reid - Angewandte Chemie, 2018 - Wiley Online Library
Die vielfältigen Anwendungen der Wasserstoffisotope (Deuterium, D, und Tritium, T) in den
physikalischen und Biowissenschaften erfordern unterschiedliche Methoden für deren …
physikalischen und Biowissenschaften erfordern unterschiedliche Methoden für deren …
K2CO3/18-Crown-6-Catalyzed Selective H/D Exchange of Heteroarenes with Bromide as a Removable Directing Group
JG Gu, CX Wang, GQ Hu, K Shen, HH Zhang - Organic Letters, 2023 - ACS Publications
The K2CO3/18-crown-6-catalyzed H/D exchange of heretoarenes in high atom% deuterium
incorporation is disclosed. The use of a weak base as a catalyst leads to excellent site …
incorporation is disclosed. The use of a weak base as a catalyst leads to excellent site …
Chiral phosphoric acid catalyzed enantioselective transfer deuteration of ketimines by use of benzothiazoline as a deuterium donor: synthesis of optically active …
T Sakamoto, K Mori, T Akiyama - Organic letters, 2012 - ACS Publications
By use of 2-deuterated benzothiazoline as a deuterium donor in combination with a chiral
phosphoric acid, the transfer deuteration of ketimine and α-iminoester took place smoothly to …
phosphoric acid, the transfer deuteration of ketimine and α-iminoester took place smoothly to …
Stereochemistry of 1, 2-elimination and proton-transfer reactions: toward a unified understanding
JR Mohrig - Accounts of Chemical Research, 2013 - ACS Publications
Many mechanistic and stereochemical studies have focused on the breaking of the C–H
bond through base-catalyzed elimination reactions. When we began our research, however …
bond through base-catalyzed elimination reactions. When we began our research, however …
A Biomimetic Synthesis of (±)‐Basiliolide B
L Min, Y Zhang, X Liang, J Huang, W Bao… - Angewandte …, 2014 - Wiley Online Library
A highly diastereoselective and practical biomimetic total synthesis of (±)‐basiliolide B has
been achieved through the study of the two proposed biosynthetic pathways (O‐methylation …
been achieved through the study of the two proposed biosynthetic pathways (O‐methylation …
Diastereoselective Total Synthesis of (±)-Basiliolide B and (±)-epi-8-Basiliolide B
X Liang, L Zhou, L Min, W Ye, W Bao… - The Journal of …, 2017 - ACS Publications
The C8 and C9 stereogenic centers of the basiliolide/transtaganolide family have been
established stereoselectively using a cyclopropane ring-opening strategy, which has been …
established stereoselectively using a cyclopropane ring-opening strategy, which has been …
Advances in light isotopes separation and catalytic labeling
LI Tianyi, WU Yutai, W Yongsheng, GU Jiarui… - CIESC …, 2024 - hgxb.cip.com.cn
Stable light isotopes such as hydrogen, carbon, nitrogen and oxygen are widely used in
medical drugs, clinical diagnosis, environmental geology and other fields. The enrichment of …
medical drugs, clinical diagnosis, environmental geology and other fields. The enrichment of …