Asthma is a heterogeneous respiratory disease characterized by usually reversible
bronchial obstruction, which is clinically expressed by different phenotypes driven by …

Airway remodeling comprises the structural changes of airway walls, induced by repeated
injury and repair processes. It is characterized by the changes of tissue, cellular, and …

BACKGROUND: Adult patients with nasal polyps often have comorbid asthma, adding to the
serious effect on the quality of life of these patients. Nasal polyps and asthma might …

Asthma is the most common chronic lower respiratory disease in childhood throughout the
world. Several guidelines and/or consensus documents are available to support medical …

Recent developments in therapeutic strategies have provided alternatives to corticosteroids
as the cornerstone treatment for managing airway inflammation in asthma. The past two …

Rationale: Ex vivo, bronchial epithelial cells from people with asthma are more susceptible
to rhinovirus infection caused by deficient induction of the antiviral protein, IFN-β …

Atopic dermatitis and psoriasis are 2 of the most common inflammatory skin diseases. They
are similar in that they are complex inherited diseases involving genes that encode immune …

Current therapies for asthma and allergy are relatively safe and effective at controlling
symptoms but do not change the chronic course of disease. There is no established method …

Omalizumab was the first, and for a long time the only available monoclonal antibody for the
add-on treatment of severe allergic asthma. In particular, omalizumab selectively targets …

abstract IgE and mast cells play a pivotal role in various allergic diseases, including asthma,
allergic rhinitis, and urticaria. Treatment with omalizumab, a monoclonal anti-IgE antibody …