The critical role of the vasculature and its repair in neurological disease states is beginning
to emerge particularly for stroke, dementia, epilepsy, Parkinson's disease, tumors and …

This article reviews recent developments in the application of cell-free DNA-based liquid
biopsies to neurological diseases. Over the past few decades, an explosion of interest in the …

Background Tranexamic acid reduces surgical bleeding and decreases mortality in patients
with traumatic extracranial bleeding. Intracranial bleeding is common after traumatic brain …

This important paper addressed a key clinical question, which was exceptionally novel at the
time of investigation. Namely, could the early administration of 1 gram of tranexamic acid …

Importance The development and expansion of intracranial hematoma are associated with
adverse outcomes. Use of tranexamic acid might limit intracranial hematoma formation, but …

Background Worldwide, over 10 million people are killed or hospitalized because of
traumatic brain injury each year. About 90% of deaths occur in low-and middle-income …

Background Traumatic brain injury (TBI) is commonly accompanied by intracranial bleeding
which can worsen after hospital admission. Tranexamic acid (TXA) has been shown to …

BACKGROUND: Tranexamic acid (TXA) has been shown to reduce blood loss in surgical
patients and the risk of death in patients with traumatic bleeding, with no apparent increase …

Traumatic brain injury (TBI) impacts over 3.17 million Americans. Management of
hemorrhage and coagulation caused by vascular disruption after TBI is critical for the …

Neuroimaging at all stages of a traumatic brain injury (TBI) provides information about gross
brain pathology. In this review, post-mortem TBI cases are matched to neuroimaging …