Discovery of a novel BLT2 antagonist for the treatment of inflammatory airway diseases
H Park, DS Harmalkar, JD Wei, S Sun, J Kwon… - European Journal of …, 2023 - Elsevier
Abstract Leukotriene B4 (LTB4) is a potent chemoattractant that can recruit and activate
immune cells such as neutrophils, eosinophils, and monocytes to sites of inflammation …
immune cells such as neutrophils, eosinophils, and monocytes to sites of inflammation …
[HTML][HTML] 12 (S)-hydroxyheptadeca-5Z, 8E, 10E-trienoic acid (12-HHT) induces cell growth and improves barrier function through BLT2 interaction in intestinal epithelial …
CE Storniolo, M Pequera, F Company… - Biochemical …, 2021 - Elsevier
Abstract 12 (S)-hydroxyheptadeca-5Z, 8E, 10E-trienoic acid (12-HHT) is an unusual product
of the cyclooxygenase pathway that is an endogenous ligand of the low-affinity receptor for …
of the cyclooxygenase pathway that is an endogenous ligand of the low-affinity receptor for …
Identification and pathophysiological roles of LTB4 receptors BLT1 and BLT2
Y Ishii, T Okuno, T Yokomizo - Lipid Signaling and Metabolism, 2020 - Elsevier
Abstract Leukotriene B 4 (LTB 4), a lipid mediator derived from arachidonic acid, is a
chemoattractant for inflammatory leukocytes. We previously identified two receptors for LTB …
chemoattractant for inflammatory leukocytes. We previously identified two receptors for LTB …