HIV-associated neurocognitive disorder—pathogenesis and prospects for treatment
In the past two decades, several advancements have improved the care of HIV-infected
individuals. Most importantly, the development and deployment of combination antiretroviral …
individuals. Most importantly, the development and deployment of combination antiretroviral …
Axonal damage: a key predictor of outcome in human CNS diseases
IM Medana, MM Esiri - Brain, 2003 - academic.oup.com
Axonal damage has recently been recognized to be a key predictor of outcome in a number
of diverse human CNS diseases, including head and spinal cord trauma, metabolic …
of diverse human CNS diseases, including head and spinal cord trauma, metabolic …
Brain deposition of beta-amyloid is a common pathologic feature in HIV positive patients
DA Green, E Masliah, HV Vinters, P Beizai, DJ Moore… - Aids, 2005 - journals.lww.com
Background: We planned to analyze the prevalence and distribution of β-amyloid deposition
in the HIV+ brain in the HAART era. Our working hypothesis is that long term survival, aging …
in the HIV+ brain in the HAART era. Our working hypothesis is that long term survival, aging …
Prevalence of cognitive disorders differs as a function of age in HIV virus infection
JT Becker, OL Lopez, MA Dew, HJ Aizenstein - Aids, 2004 - journals.lww.com
Objectives: Ten per cent of all new cases of AIDS in the United States are in persons older
than 50 years. This is particularly problematical in the case of the neuropsychiatric …
than 50 years. This is particularly problematical in the case of the neuropsychiatric …
[HTML][HTML] Increased accumulation of intraneuronal amyloid β in HIV-infected patients
CL Achim, A Adame, W Dumaop, IP Everall… - Journal of Neuroimmune …, 2009 - Springer
In recent years, human immunodeficiency virus (HIV)-infected patients under highly active
anti-retroviral therapy (HAART) regimens have shown a markedly improved general clinical …
anti-retroviral therapy (HAART) regimens have shown a markedly improved general clinical …
Neuroprotective and anti–human immunodeficiency virus activity of minocycline
MC Zink, J Uhrlaub, J DeWitt, T Voelker, B Bullock… - Jama, 2005 - jamanetwork.com
ContextThe prevalence of human immunodeficiency virus (HIV) central nervous system
(CNS) disease has not decreased despite highly active antiretroviral therapy. Current …
(CNS) disease has not decreased despite highly active antiretroviral therapy. Current …
[HTML][HTML] Cerebrospinal fluid (CSF) neuronal biomarkers across the spectrum of HIV infection: hierarchy of injury and detection
J Peterson, M Gisslen, H Zetterberg, D Fuchs… - PloS one, 2014 - journals.plos.org
The character of central nervous system (CNS) HIV infection and its effects on neuronal
integrity vary with evolving systemic infection. Using a cross-sectional design and archived …
integrity vary with evolving systemic infection. Using a cross-sectional design and archived …
[HTML][HTML] Amyloid and tau cerebrospinal fluid biomarkers in HIV infection
Background Because of the emerging intersections of HIV infection and Alzheimer's
disease, we examined cerebrospinal fluid (CSF) biomarkers related of amyloid and tau …
disease, we examined cerebrospinal fluid (CSF) biomarkers related of amyloid and tau …
Diffusion tensor imaging with quantitative fibre tracking in HIV infection and alcoholism comorbidity: synergistic white matter damage
A Pfefferbaum, MJ Rosenbloom, E Adalsteinsson… - Brain, 2007 - academic.oup.com
A substantial proportion of individuals infected with human immunodeficiency virus (HIV)
also abuse alcohol. Given that each condition can disrupt brain structural integrity, with a …
also abuse alcohol. Given that each condition can disrupt brain structural integrity, with a …
Involvement of quinolinic acid in AIDS dementia complex
Human immunodeficiency virus (HIV) infection is often complicated by the development of
acquired immunodeficiency syndrome (AIDS) dementia complex (ADC). Quinolinic acid …
acquired immunodeficiency syndrome (AIDS) dementia complex (ADC). Quinolinic acid …